CSF3, colony stimulating factor 3, 1440

N. diseases: 687; N. variants: 4
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0025202
Disease: melanoma
melanoma
0.330 Biomarker disease BEFREE We hypothesized that expression of CD114, the cell surface receptor for granulocyte-colony stimulating factor (G-CSF), would be associated with melanoma tumor cell growth and response to treatment. 26124323 2015
CUI: C0025202
Disease: melanoma
melanoma
0.330 Therapeutic disease CTD_human We believe that the brilliant CR, the long duration of the disease-free intervals and the long survival in at least three of eight patients should encourage further research on BOLD with G-CSF for the treatment of advanced melanoma. 16120623 2005
CUI: C0025202
Disease: melanoma
melanoma
0.330 Therapeutic disease CTD_human Low-dose outpatient chemobiotherapy with temozolomide, granulocyte-macrophage colony stimulating factor, interferon-alpha2b, and recombinant interleukin-2 for the treatment of metastatic melanoma. 16260693 2005
CUI: C0025202
Disease: melanoma
melanoma
0.330 AlteredExpression disease BEFREE Furthermore, no obvious autocrine or paracrine effects of this ectopic G-CSF expression on the melanoma lines' growth or metastasis were apparent, as all of the G-CSF-expressing lines lacked the G-CSF receptor and injections of purified recombinant G-CSF exerted no stimulatory effects on their tumorigenicity, latency, growth, or metastasis in Scid mice. 9060833 1997
CUI: C0025202
Disease: melanoma
melanoma
0.330 Biomarker disease BEFREE Northern blots of LD-1 RNA hybridized strongly with oligonucleotide probes based on the published sequences for human G-CSF, but not with a probe based on the human GM-CSF sequence. 3498641 1987