Lupus Erythematosus, Systemic
|
0.320 |
GeneticVariation
|
disease |
BEFREE |
Autoimmune risk loci of IL12RB2, IKZF1, XKR6, TMEM39A and CSK in Chinese patients with systemic lupus erythematosus.
|
25720506 |
2015 |
Lupus Erythematosus, Systemic
|
0.320 |
Biomarker
|
disease |
CTD_human |
We identified an association of CSK with systemic lupus erythematosus (SLE) and refined its location to the intronic polymorphism rs34933034 (odds ratio (OR) = 1.32; P = 1.04 × 10(-9)).
|
23042117 |
2012 |
Lupus Erythematosus, Systemic
|
0.320 |
GeneticVariation
|
disease |
BEFREE |
We identified an association of CSK with systemic lupus erythematosus (SLE) and refined its location to the intronic polymorphism rs34933034 (odds ratio (OR) = 1.32; P = 1.04 × 10(-9)).
|
23042117 |
2012 |
Libman-Sacks Disease
|
0.300 |
Biomarker
|
disease |
CTD_human |
CSK regulatory polymorphism is associated with systemic lupus erythematosus and influences B-cell signaling and activation.
|
23042117 |
2012 |
Hyperalgesia
|
0.300 |
Biomarker
|
phenotype |
CTD_human |
Osteoclasts play a part in pain due to the inflammation adjacent to bone.
|
16769263 |
2006 |
Allodynia
|
0.300 |
Biomarker
|
phenotype |
CTD_human |
Osteoclasts play a part in pain due to the inflammation adjacent to bone.
|
16769263 |
2006 |
Hyperalgesia, Primary
|
0.300 |
Biomarker
|
phenotype |
CTD_human |
Osteoclasts play a part in pain due to the inflammation adjacent to bone.
|
16769263 |
2006 |
Hyperalgesia, Secondary
|
0.300 |
Biomarker
|
phenotype |
CTD_human |
Osteoclasts play a part in pain due to the inflammation adjacent to bone.
|
16769263 |
2006 |
Tactile Allodynia
|
0.300 |
Biomarker
|
phenotype |
CTD_human |
Osteoclasts play a part in pain due to the inflammation adjacent to bone.
|
16769263 |
2006 |
Hyperalgesia, Thermal
|
0.300 |
Biomarker
|
phenotype |
CTD_human |
Osteoclasts play a part in pain due to the inflammation adjacent to bone.
|
16769263 |
2006 |
Mechanical Allodynia
|
0.300 |
Biomarker
|
phenotype |
CTD_human |
Osteoclasts play a part in pain due to the inflammation adjacent to bone.
|
16769263 |
2006 |
Liver carcinoma
|
0.220 |
Biomarker
|
disease |
BEFREE |
Our data demonstrated that the inhibitory effect of ITGA9 on HCC cell motility was associated with reduced phosphorylation of focal adhesion kinase (FAK) and c-Src tyrosine kinase (Src), disrupted focal adhesion reorganization, and decreased Rac1 and RhoA activity.
|
29951557 |
2018 |
Liver carcinoma
|
0.220 |
AlteredExpression
|
disease |
BEFREE |
And the inhibitory effects of DPT on HCC cell motility were associated with dysregulated focal adhesion assembly, decreased RhoA activity and reduced focal adhesion kinase (FAK) and c-Src tyrosine kinase (Src) phosphorylation, and all of these alterations required the involvement of integrin signaling.
|
25149533 |
2014 |
Liver carcinoma
|
0.220 |
Biomarker
|
disease |
RGD |
A single immunoreactive band at 50 kd was detected with Csk antibody in normal liver (NL), chronic hepatitis (CH), and nontumorous cirrhotic (NTC) segments of HCC of patients and LEC rats.
|
9918913 |
1999 |
Hyperplasia
|
0.200 |
Biomarker
|
phenotype |
RGD |
Down-regulation of the tumor suppressor gene C-terminal Src kinase: an early event during premalignant colonic epithelial hyperproliferation.
|
15961079 |
2005 |
Liver neoplasms
|
0.200 |
Biomarker
|
group |
RGD |
Reduced C-terminal Src kinase (Csk) activities in hepatocellular carcinoma.
|
9918913 |
1999 |
Hepatoblastoma
|
0.200 |
Biomarker
|
disease |
RGD |
Reduced C-terminal Src kinase (Csk) activities in hepatocellular carcinoma.
|
9918913 |
1999 |
Malignant neoplasm of liver
|
0.200 |
Biomarker
|
disease |
RGD |
Reduced C-terminal Src kinase (Csk) activities in hepatocellular carcinoma.
|
9918913 |
1999 |
Hepatoblastoma Caused By Somatic Mutation
|
0.200 |
Biomarker
|
disease |
RGD |
Reduced C-terminal Src kinase (Csk) activities in hepatocellular carcinoma.
|
9918913 |
1999 |
Birth Weight
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors.
|
31043758 |
2019 |
Systemic Scleroderma
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways.
|
31672989 |
2019 |
Waist-Hip Ratio
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry.
|
30239722 |
2019 |
Systolic Pressure
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Trans-ethnic association study of blood pressure determinants in over 750,000 individuals.
|
30578418 |
2019 |
Diastolic blood pressure
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure.
|
29455858 |
2018 |
Diastolic blood pressure
|
0.100 |
GeneticVariation
|
phenotype |
GWASCAT |
Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries.
|
29912962 |
2018 |