CDAN1, codanin 1, 146059

N. diseases: 77; N. variants: 15
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0015672
Disease: Fatigue
Fatigue
0.030 Biomarker phenotype BEFREE For the safety analysis (n = 20), treatment-related grade 1 adverse events included fatigue (n = 6), chills (n = 2), and headache (n = 1), with no organ damage and no DLT. 30705966 2019
CUI: C0015672
Disease: Fatigue
Fatigue
0.030 GeneticVariation phenotype BEFREE Moderate/severe toxicities included fatigue (DLT at veliparib 400mg BID), diarrhea, and thrombocytopenia. 26848151 2016
CUI: C0015672
Disease: Fatigue
Fatigue
0.030 Biomarker phenotype BEFREE Two of 6 patients in cohort -1 had a DLT (grade 3 pulmonary embolism and grade 3 fatigue); thus, the study was terminated. 26149476 2015