IL34, interleukin 34, 146433

N. diseases: 103; N. variants: 5
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0003864
Disease: Arthritis
Arthritis
0.060 AlteredExpression disease BEFREE Interestingly, the pSS patients with arthritis had higher levels of IL-34 compared with the no-arthritis patients. 31823505 2020
CUI: C0003864
Disease: Arthritis
Arthritis
0.060 Biomarker disease BEFREE To date, there are numerous studies showing IL-34 involvement and association with many aspects of inflammatory arthritis. 31126875 2019
CUI: C0003864
Disease: Arthritis
Arthritis
0.060 Biomarker disease BEFREE In conclusion, IL-34 acts as a proinflammatory factor, aggravating the severity of arthritis in CIA mice by inducing the production of IL-17. 29664689 2018
CUI: C0003864
Disease: Arthritis
Arthritis
0.060 Biomarker disease BEFREE Taken together, we infer that IL-34 has a role in stimulating fibrocyte proliferation and activation during arthritis, thereby contributing to both onset of RA and systemic spread of disease. 28972432 2017
CUI: C0003864
Disease: Arthritis
Arthritis
0.060 Biomarker disease BEFREE Furthermore, the relatively newer cytokines such as IL-32, IL-34 and IL-35 are being investigated for their potential role in the pathogenesis and treatment of arthritis. 25561237 2014
CUI: C0003864
Disease: Arthritis
Arthritis
0.060 AlteredExpression disease BEFREE This work for the first time identifies IL-34 expression in the synovial tissue of patients with arthritis. 22039170 2012