IL34, interleukin 34, 146433

N. diseases: 103; N. variants: 5
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
0.040 AlteredExpression disease BEFREE Indeed, IL-34 has been documented to be highly expressed in inflamed synovium of rheumatoid arthritis (RA) and knee osteoarthritis (OA) patients, which are recognized as inflammatory arthritis. 31126875 2019
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
0.040 AlteredExpression disease BEFREE The correlation between SF IL-34 levels and WOMAC scores was still significant after adjusting for confounding factors (<i>B</i> = 0.020, 95% CI: 0.001-0.038; <i>P</i> = 0.035) in OA patients. 30159102 2018
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
0.040 Biomarker disease BEFREE In contrast to almost no detectable IL-34 in osteoarthritis (OA) and healthy serum, IL-34 could be detected in 93 out of the 125 RA cases (74.4%). 23421370 2013
CUI: C0029408
Disease: Degenerative polyarthritis
Degenerative polyarthritis
0.040 AlteredExpression disease BEFREE The production of IL-34 in FLS was up-regulated by TNFα in RA samples compared with osteoarthritis (OA) patients. 22264405 2012