CSTA, cystatin A, 1475

N. diseases: 97; N. variants: 6
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.340 Biomarker phenotype BEFREE Competing risk analysis identified three genes that were downregulated differentially in the patients with brain metastases versus non-brain metastatic disease: CD37 (0.017), cystatin A (0.022), and IL-23A (0.027). 30854931 2019
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.340 Biomarker phenotype BEFREE A significant positive relationship of stefin A and stefin B was found with node metastasis, tumor size, and Edmondson grade for HCC. 26753874 2016
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.340 Biomarker phenotype CTD_human Identification of candidate nasopharyngeal carcinoma serum biomarkers by cancer cell secretome and tissue transcriptome analysis: potential usage of cystatin A for predicting nodal stage and poor prognosis. 20461718 2010
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.340 AlteredExpression phenotype BEFREE We propose that Stefin A, as a cysteine cathepsin inhibitor, may be a marker of increased cathepsin activity in metastases. 17985332 2008
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.340 AlteredExpression phenotype LHGDN We propose that Stefin A, as a cysteine cathepsin inhibitor, may be a marker of increased cathepsin activity in metastases. 17985332 2008
CUI: C0027627
Disease: Neoplasm Metastasis
Neoplasm Metastasis
0.340 Biomarker phenotype BEFREE Our data strongly indicate that stefin A plays an important role in the growth, angiogenesis, invasion, and metastasis of human esophageal squamous cell carcinoma cells and suggest that stefin A may be useful in cancer therapy. 16361563 2005