Disease: Liver Cirrhosis ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023890
Disease: Liver Cirrhosis
Liver Cirrhosis 		0.350 Biomarker disease CTD_human Gene Expression Patterns Associated With Histopathology in Toxic Liver Fibrosis. 26396155 2016
CUI: C0023890
Disease: Liver Cirrhosis
Liver Cirrhosis 		0.350 AlteredExpression disease BEFREE Of note, HCC patients without underlying cirrhosis (n=8) had CTGF levels (13.5±13.2 μg/L) comparable to those in healthy controls. 23501329 2013
CUI: C0023890
Disease: Liver Cirrhosis
Liver Cirrhosis 		0.350 Biomarker disease BEFREE Serum CCN2 concentrations were, respectively, 4.0- or 4.9-fold higher in patients with CHB or active liver cirrhosis as compared to healthy individuals (P < 0.01). 22611323 2012
CUI: C0023890
Disease: Liver Cirrhosis
Liver Cirrhosis 		0.350 Biomarker disease BEFREE To expand the results to other aetiologies, a separate cohort of CLD patients (n = 129) was evaluated, showing higher serum CTGF than healthy controls and again an association with advanced stages of liver cirrhosis (Child B and C). 19243500 2009
CUI: C0023890
Disease: Liver Cirrhosis
Liver Cirrhosis 		0.350 AlteredExpression disease BEFREE Six (8%) of the 76 patients with IPH had serum CTGF levels greater than 80 ng/mL, far exceeding the level of any patient with cirrhosis. 17622321 2007
CUI: C0023890
Disease: Liver Cirrhosis
Liver Cirrhosis 		0.350 Biomarker disease CTD_human Profibrogenic transforming growth factor-beta/activin receptor-like kinase 5 signaling via connective tissue growth factor expression in hepatocytes. 17657819 2007
CUI: C0023890
Disease: Liver Cirrhosis
Liver Cirrhosis 		0.350 Biomarker disease CTD_human Inhibition of connective tissue growth factor by siRNA prevents liver fibrosis in rats. 16652398 2006
CUI: C0023890
Disease: Liver Cirrhosis
Liver Cirrhosis 		0.350 Biomarker disease BEFREE In experimental models of liver fibrosis, CTGF accumulated in parallel with the development of septal fibrosis and cirrhosis. 10498649 1999