CTNNB1, catenin beta 1, 1499

N. diseases: 1368; N. variants: 68
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma
0.400 AlteredExpression disease BEFREE Mutations in PIK3CA and CTNNB1 occurred more frequently in cases of sporadic EC compared with LS-associated EC. 23760948 2013
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma
0.400 AlteredExpression disease BEFREE MTT assay is performed to determine the growth inhibition ratio of the DNA methyltransferase inhibitor 5-AZA for endometrial carcinoma cells, and the real-time fluorescence quantification PCR (qRT-PCR) was used to detect the mRNA expression of SOX17, β-catenin, and CyclinD1 in endometrial carcinoma tissues before and after using 5-AZA to treat the endometrial carcinoma cell line. 31543512 2019
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma
0.400 AlteredExpression disease BEFREE Ectopic overexpression of Gli1 into endometrial cancer cells led to reduced expression of beta-catenin in cell cytoplasm and increased expression of beta-catenin in the nuclei. 19329935 2009
CUI: C0476089
Disease: Endometrial Carcinoma
Endometrial Carcinoma
0.400 CausalMutation disease CGI