Squamous cell carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Casticin inhibits invasion and proliferation via downregulation of β-catenin and reversion of EMT in oral squamous cell carcinoma.
|
31318467 |
2019 |
Squamous cell carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
lncRNA PLAC2 activated by H3K27 acetylation promotes cell proliferation and invasion via the activation of Wnt/β‑catenin pathway in oral squamous cell carcinoma.
|
30720068 |
2019 |
Squamous cell carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
These results were related to endogenous p63-p300 complex formation and Wnt/β-catenin-responsive gene regulation by p63 in squamous cell carcinoma lines.
|
30986748 |
2019 |
Squamous cell carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Comparative study of β-catenin and CD44 immunoexpression in oral lichen planus and squamous cell carcinoma.
|
29693240 |
2018 |
Squamous cell carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Consistently, SOX30 is negatively associated with the expression of Wnt-signaling and metastasis-related gene CTNNB1 (β-catenin) in ADC, but not in SCC.
|
30514297 |
2018 |
Squamous cell carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Impact of Small Molecules on β-Catenin and E-Cadherin Expression in HPV16-positive and -negative Squamous Cell Carcinomas.
|
28551620 |
2017 |
Squamous cell carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
A total of 87 paraffin-embedded cervical sections with distinct cervical intraepithelial neoplasia (CIN) stages (chronic cervicitis, CIN 1, CIN 2, CIN 3 and invasive squamous cell carcinoma) were collected between June 2004 and October 2012 The mRNA expression level of Chibby and β-catenin was determined using the polymerase chain reaction.
|
29181101 |
2017 |
Squamous cell carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The aim of our study was to analyze the immunohistochemical expression of β-catenin, E-cadherin and Snail, depending on clinico-morphological aspects of the laryngeal squamous cell carcinomas.
|
29250652 |
2017 |
Squamous cell carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Prognostic significance of E-cadherin and β-catenin expression in HPV-negative oropharyngeal squamous cell carcinomas.
|
28815780 |
2017 |
Squamous cell carcinoma
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Dramatic response of CTNNB1 and VEGFR-2 mutant temporal bone squamous cell carcinoma to bevacizumab in combination with pemetrexed.
|
28915721 |
2017 |
Squamous cell carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Overexpression of β-catenin and cyclin D1 was significantly associated with poor overall survival (p = 0.003 and p = 0.0009, respectively; log rank test) in squamous cell carcinomas, not in adenocarcinomas.
|
27498289 |
2016 |
Squamous cell carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Overexpression of β-Catenin Induces Cisplatin Resistance in Oral Squamous Cell Carcinoma.
|
27529071 |
2016 |
Squamous cell carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Aberrant Wnt regulation, detectable by nuclear translocation of beta-catenin, is a hallmark of many cancers including skin squamous cell carcinomas (SCCs).
|
25403422 |
2015 |
Squamous cell carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
The high expression of TC1 (C8orf4) was correlated with the expression of β-catenin and cyclin D1 and the progression of squamous cell carcinomas of the tongue.
|
25869879 |
2015 |
Squamous cell carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
We were able to show incomplete EGF-induced EMT with β-catenin expression in p16-positive SCC.
|
25503133 |
2014 |
Squamous cell carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
E-cadherin and β-catenin immunostaining showed no prognostic value for basaloid and conventional squamous cell carcinomas.
|
24893577 |
2014 |
Squamous cell carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Although altered regulation of the Wnt pathway via beta-catenin is a frequent event in several human cancers, its potential implications in oral/oropharyngeal squamous cell carcinomas (OSCC/OPSCC) are largely unexplored.
|
24511551 |
2014 |
Squamous cell carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Remarkably, high Wnt/β-catenin and low Bmp signalling also characterize human salivary gland SCC and head and neck SCC in general.
|
23736260 |
2013 |
Squamous cell carcinoma
|
0.100 |
AlteredExpression
|
disease |
BEFREE |
Expression of TRIM29 in squamous cell carcinoma (SC) tissues was positively correlated with abnormal expression of β-catenin, histological grade, tumor-node-metastasis (TNM) stage, and lymph node metastasis and that was positively correlated with tumor size, histological grading, TNM stage and lymph node metastasis in adenocarcinoma (AC).
|
22721621 |
2012 |
Squamous cell carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
These observations are recapitulated in normal human bronchial epithelial cells in vitro following both pharmacological β-catenin activation and E-cadherin inhibition, and mirrored our findings in preinvasive SCCs.
|
22081448 |
2012 |
Squamous cell carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
An increase in β-catenin and Ki-67 expressions was observed from dysplasias to poorly differentiated SCC.
|
21932035 |
2011 |
Squamous cell carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
In addition, we show that ΔNp63 and β-catenin are frequently coexpressed and accumulated in oesophageal SCC, but not in HCC.
|
21643019 |
2011 |
Squamous cell carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
Human FAT1 cadherin controls cell migration and invasion of oral squamous cell carcinoma through the localization of β-catenin.
|
21617878 |
2011 |
Squamous cell carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
To clarify the role of cytoplasmic accumulation of β-catenin in oral squamous cell carcinoma (SCC), the cDNA of a mutant form of β-catenin that lacks the entire region with the glycogen synthase kinase-3 β (GSK-3β)-specific phosphorylation site was transfected into Ca9-22 cells whose β-catenin had been expressed predominantly at the membrane, and permanent cell lines expressing aberrant β-catenin in the cytoplasm and nucleus were produced.
|
20878057 |
2010 |
Squamous cell carcinoma
|
0.100 |
Biomarker
|
disease |
BEFREE |
We show for the first time that the putative Wnt/beta-catenin targets Shh and JAG2 control beta-catenin signaling in the adult tongue epithelium, a function that is partially lost in lingual SCC.
|
20508033 |
2010 |