CTNNB1, catenin beta 1, 1499

N. diseases: 1368; N. variants: 68
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
0.440 Biomarker disease BEFREE Knockdown of the expression of PTEN altered the expression of p‑AKT, p‑glycogen synthase kinase 3β and β‑catenin, which are genes that have been reported to be involved in the development of gastric adenocarcinoma. 29512701 2018
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
0.440 AlteredExpression disease BEFREE DKK1 and Wnt/β-catenin-dependent activation of MMP7 induces T-DM1 resistance and leads to the poor prognosis of gastric adenocarcinoma, which might be a novel potential therapeutical target for T-DM1 resistant gastric adenocarcinoma. 30501604 2018
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
0.440 AlteredExpression disease BEFREE Specific indexes include the pathological characteristics of gastric neoplasia, Helicobacter pylori infection, β-catenin mutation status, and methylation status of Wnt antagonist genes.There was significant difference of β-catenin expression in patient with NGT, LGA, HGA, and GAC, the results respectively were 4.2%, 41.7%, 83.3%, and 91.7%. 30593147 2018
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
0.440 GeneticVariation disease CLINVAR Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity. 26619011 2016
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
0.440 Biomarker disease BEFREE Expression of APC, β-catenin and E-cadherin in Tunisian patients with gastric adenocarcinoma: clinical significance. 24197976 2014
CUI: C0278701
Disease: Gastric Adenocarcinoma
Gastric Adenocarcinoma
0.440 CausalMutation disease CGI