CTNNB1, catenin beta 1, 1499

N. diseases: 1368; N. variants: 68
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0334558
Disease: Malignant odontogenic tumor
Malignant odontogenic tumor
0.020 GeneticVariation disease BEFREE CTNNB1 mutation was only found in one OC case, whereas three of six (50%) ameloblastoma cases and two out of eight (25%) OC cases had APC mutations within the mutational cluster region. 18486530 2009
CUI: C0334558
Disease: Malignant odontogenic tumor
Malignant odontogenic tumor
0.020 AlteredExpression disease BEFREE Immunohistochemically, all follicular ameloblastomas and one primary intraosseous odontogenic carcinoma exhibited focal and moderate nuclear/cytoplasmic expression of CTNNB1, whereas the plexiform ameloblastoma and the remaining two malignant odontogenic tumors had entirely membranous expression. 17096730 2006