|
Autistic Disorder
|
0.340 |
Biomarker
|
disease |
BEFREE |
Thus, additional larger studies will be necessary to determine whether CNTN4 functions as an autism susceptibility locus in combination with other genetic and/or environmental factors.
|
21308999 |
2011 |
|
Autistic Disorder
|
0.340 |
Biomarker
|
disease |
BEFREE |
The contactin (CNTN) family of Ig cell adhesion molecules (IgCAMs) harbours at least three members that have genetically been implicated in autism: CNTN4, CNTN5, and CNTN6.
|
23872404 |
2013 |
|
Autistic Disorder
|
0.340 |
GeneticVariation
|
disease |
BEFREE |
We focused our initial analysis on CNTNAP2 based on our demonstration of disruption of Contactin 4 (CNTN4) in a patient with ASD; the recent finding of rare homozygous mutations in CNTNAP2 leading to intractable seizures and autism; and in situ and biochemical analyses reported herein that confirm expression in relevant brain regions and demonstrate the presence of CNTNAP2 in the synaptic plasma membrane fraction of rat forebrain lysates.
|
18179895 |
2008 |
|
Autistic Disorder
|
0.340 |
GeneticVariation
|
disease |
BEFREE |
Our results suggest that rare copy number variations (CNVs) in CNTN4 may also influence autism susceptibility in Asian populations.
|
22750301 |
2012 |
|
Autistic Disorder
|
0.340 |
Biomarker
|
disease |
CTD_human |
Disruption of contactin 4 in three subjects with autism spectrum disorder.
|
18349135 |
2009 |
|
Alcoholic Intoxication, Chronic
|
0.310 |
Biomarker
|
disease |
PSYGENET |
Bipolar disorder with alcohol dependence and other co-morbidities was associated with SNP rs2727943 (p = 3.3×10⁻⁸) on chromosome 3p26.3 located between the genes contactin-4 precursor (BIG-2) and contactin 6 (CNTN6).
|
22205951 |
2011 |
|
Alcoholic Intoxication, Chronic
|
0.310 |
GeneticVariation
|
disease |
BEFREE |
Bipolar disorder with alcohol dependence and other co-morbidities was associated with SNP rs2727943 (p = 3.3×10⁻⁸) on chromosome 3p26.3 located between the genes contactin-4 precursor (BIG-2) and contactin 6 (CNTN6).
|
22205951 |
2011 |
|
Bipolar Disorder
|
0.300 |
Biomarker
|
disease |
PSYGENET |
Bipolar disorder with alcohol dependence and other co-morbidities was associated with SNP rs2727943 (p = 3.3×10⁻⁸) on chromosome 3p26.3 located between the genes contactin-4 precursor (BIG-2) and contactin 6 (CNTN6).
|
22205951 |
2011 |
|
Colorectal Carcinoma
|
0.300 |
GeneticVariation
|
disease |
UNIPROT |
|
|
|
|
Child Development Deviations
|
0.300 |
Biomarker
|
disease |
CTD_human |
Disruption of contactin 4 (CNTN4) results in developmental delay and other features of 3p deletion syndrome.
|
15106122 |
2004 |
|
Child Development Disorders, Specific
|
0.300 |
Biomarker
|
disease |
CTD_human |
Disruption of contactin 4 (CNTN4) results in developmental delay and other features of 3p deletion syndrome.
|
15106122 |
2004 |
|
Lip and Oral Cavity Carcinoma
|
0.110 |
GeneticVariation
|
disease |
BEFREE |
Single nucleotide polymorphisms in an Indian cohort and association of CNTN4, MMP2 and SNTB1 variants with oral cancer.
|
28595731 |
2017 |
|
Lip and Oral Cavity Carcinoma
|
0.110 |
GeneticVariation
|
disease |
CLINVAR |
|
|
|
|
gallbladder neoplasm
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
A genome-wide association study identifies SNP in DCC is associated with gallbladder cancer in the Japanese population.
|
22318345 |
2012 |
|
Chronic Obstructive Airway Disease
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Body mass index change in gastrointestinal cancer and chronic obstructive pulmonary disease is associated with Dedicator of Cytokinesis 1.
|
28044437 |
2017 |
|
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Association of Schizophrenia Risk With Disordered Niacin Metabolism in an Indian Genome-wide Association Study.
|
31268507 |
2019 |
|
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association study of schizophrenia in Ashkenazi Jews.
|
26198764 |
2015 |
|
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia.
|
28540026 |
2017 |
|
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.
|
29483656 |
2018 |
|
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Pleiotropic Meta-Analysis of Cognition, Education, and Schizophrenia Differentiates Roles of Early Neurodevelopmental and Adult Synaptic Pathways.
|
31374203 |
2019 |
|
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Biological insights from 108 schizophrenia-associated genetic loci.
|
25056061 |
2014 |
|
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-Wide Association Study Detected Novel Susceptibility Genes for Schizophrenia and Shared Trans-Populations/Diseases Genetic Effect.
|
30285260 |
2019 |
|
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Five novel loci associated with antipsychotic treatment response in patients with schizophrenia: a genome-wide association study.
|
29503163 |
2018 |
|
Schizophrenia
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Genome-wide association analysis identifies 30 new susceptibility loci for schizophrenia.
|
28991256 |
2017 |
|
Malignant neoplasm of gallbladder
|
0.100 |
GeneticVariation
|
disease |
GWASDB |
A genome-wide association study identifies SNP in DCC is associated with gallbladder cancer in the Japanese population.
|
22318345 |
2012 |