KLB, klotho beta, 152831

N. diseases: 53; N. variants: 6
Disease: Diarrhea ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011991
Disease: Diarrhea
Diarrhea 		0.020 GeneticVariation phenotype BEFREE Variants in KLB and FGFR4 genes (that determine the functional re-uptake of BA in the portal circulation by hepatocytes) are also demonstrated to be associated with (75)SeHCAT retention, confirming a second potential mechanism for the development of BA diarrhea. 27018117 2016
CUI: C0011991
Disease: Diarrhea
Diarrhea 		0.020 GeneticVariation phenotype BEFREE Thus exome sequencing identified additional variants in KLB and FGFR4 associated with bile acids or colonic transit in IBS-D. 24200957 2014