Cardiomyopathy, Dilated
|
0.580 |
GeneticVariation
|
group |
BEFREE |
To introduce an animal model, we investigated the β1-AAB associated autoimmunity in Doberman Pinscher (DP) with dilated cardiomyopathy, which has similarities to human DCM.
|
31276517 |
2019 |
Cardiomyopathy, Dilated
|
0.580 |
Biomarker
|
group |
BEFREE |
Agonistically acting autoantibodies directed against the adrenergic beta-1 receptor (beta1-AABs) are a pathogenic factor in diseases of the heart and circulatory system such as dilated cardiomyopathy.
|
30539571 |
2019 |
Cardiomyopathy, Dilated
|
0.580 |
Biomarker
|
group |
BEFREE |
Autoantibodies to beta-1 adrenergic receptor have been reported in adult patients with dilated cardiomyopathy (DCM).
|
30468641 |
2019 |
Cardiomyopathy, Dilated
|
0.580 |
Biomarker
|
group |
BEFREE |
Autoantibodies directed against the second extracellular loop of the cardiac β1-adrenergic receptor (β1-AR) are thought to contribute to the pathogenesis of dilated cardiomyopathy (DCM) and Chagas heart disease.
|
22811559 |
2012 |
Cardiomyopathy, Dilated
|
0.580 |
AlteredExpression
|
group |
BEFREE |
The main findings were 1) the expression of the α(1A)-AR in the LV positively correlates with LVEF; 2) the expression of GRK3 and GRK5 inversely correlates with LVESD and LVEDD, supporting previous observations about a protective role for both kinases in failing hearts; and 3) β(1)-AR expression is downregulated in the LV and RV of IC, in the LV of DC, and in the RV of NINDC.
|
22685168 |
2012 |
Cardiomyopathy, Dilated
|
0.580 |
GeneticVariation
|
group |
LHGDN |
Beta1- and alpha2c-adrenoreceptor variants as predictors of clinical aspects of dilated cardiomyopathy in people of African ancestry.
|
18776959 |
2008 |
Cardiomyopathy, Dilated
|
0.580 |
Biomarker
|
group |
RGD |
Cardioprotective and survival benefits of long-term combined therapy with beta2 adrenoreceptor (AR) agonist and beta1 AR blocker in dilated cardiomyopathy postmyocardial infarction.
|
18287209 |
2008 |
Cardiomyopathy, Dilated
|
0.580 |
GeneticVariation
|
group |
LHGDN |
Beta1- and beta2-adrenergic receptor polymorphisms affect susceptibility to idiopathic dilated cardiomyopathy.
|
17667029 |
2007 |
Cardiomyopathy, Dilated
|
0.580 |
GeneticVariation
|
group |
BEFREE |
In vitro, the Gly389 variant of beta1-AR mediates less adenylyl cyclase activities than the Arg389 variant, so Arg389Gly polymorphism was investigated with regard to the genesis, progression, or arrhythmogenesis of dilated cardiomyopathy (DCM).
|
12197595 |
2002 |
Cardiomyopathy, Dilated
|
0.580 |
GeneticVariation
|
group |
LHGDN |
Suppressive effect of the Gly389 allele of the beta1-adrenergic receptor gene on the occurrence of ventricular tachycardia in dilated cardiomyopathy.
|
12197595 |
2002 |
Cardiomyopathy, Dilated
|
0.580 |
Biomarker
|
group |
CTD_human |
Diminished responsiveness of Gs-coupled receptors in severely failing human hearts: no difference in dilated versus ischemic cardiomyopathy.
|
9554809 |
1998 |