CYBB, cytochrome b-245 beta chain, 1536

N. diseases: 28; N. variants: 73
Source: CURATED ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0023893
Disease: Liver Cirrhosis, Experimental
Liver Cirrhosis, Experimental 		0.300 Biomarker disease CTD_human Systems level analysis and identification of pathways and networks associated with liver fibrosis. 25380136 2014
CUI: C0023212
Disease: Left-Sided Heart Failure
Left-Sided Heart Failure 		0.300 Biomarker disease CTD_human MnSOD protects against COX1-mediated endothelial dysfunction in chronic heart failure. 20304815 2010
CUI: C0033687
Disease: Proteinuria
Proteinuria 		0.300 Biomarker phenotype CTD_human Protection of podocytes from hyperhomocysteinemia-induced injury by deletion of the gp91phox gene. 20116427 2010
CUI: C0235527
Disease: Heart Failure, Right-Sided
Heart Failure, Right-Sided 		0.300 Biomarker disease CTD_human MnSOD protects against COX1-mediated endothelial dysfunction in chronic heart failure. 20304815 2010
CUI: C1959583
Disease: Myocardial Failure
Myocardial Failure 		0.300 Biomarker disease CTD_human MnSOD protects against COX1-mediated endothelial dysfunction in chronic heart failure. 20304815 2010
CUI: C1961112
Disease: Heart Decompensation
Heart Decompensation 		0.300 Biomarker phenotype CTD_human MnSOD protects against COX1-mediated endothelial dysfunction in chronic heart failure. 20304815 2010
CUI: C0002152
Disease: Alloxan Diabetes
Alloxan Diabetes 		0.300 Biomarker disease CTD_human Resveratrol improves endothelial function: role of TNF{alpha} and vascular oxidative stress. 19478208 2009
CUI: C0027055
Disease: Myocardial Reperfusion Injury
Myocardial Reperfusion Injury 		0.300 Biomarker phenotype CTD_human Effects of quercetin on gene and protein expression of NOX and NOS after myocardial ischemia and reperfusion in rabbit. 19207477 2009
CUI: C0038433
Disease: Streptozotocin Diabetes
Streptozotocin Diabetes 		0.300 Biomarker disease CTD_human Resveratrol improves endothelial function: role of TNF{alpha} and vascular oxidative stress. 19478208 2009
CUI: C0393953
Disease: Anterior Cerebral Circulation Infarction
Anterior Cerebral Circulation Infarction 		0.300 Biomarker phenotype CTD_human Inhibition of NADPH oxidase is neuroprotective after ischemia-reperfusion. 19417757 2009
CUI: C0751952
Disease: Anterior Circulation Brain Infarction
Anterior Circulation Brain Infarction 		0.300 Biomarker phenotype CTD_human Inhibition of NADPH oxidase is neuroprotective after ischemia-reperfusion. 19417757 2009
CUI: C0751953
Disease: Brain Infarction, Posterior Circulation
Brain Infarction, Posterior Circulation 		0.300 Biomarker phenotype CTD_human Inhibition of NADPH oxidase is neuroprotective after ischemia-reperfusion. 19417757 2009
CUI: C0751954
Disease: Venous Infarction, Brain
Venous Infarction, Brain 		0.300 Biomarker phenotype CTD_human Inhibition of NADPH oxidase is neuroprotective after ischemia-reperfusion. 19417757 2009
CUI: C0751955
Disease: Brain Infarction
Brain Infarction 		0.300 Biomarker disease CTD_human At 24 h of reperfusion, the gp91(phox)-/- and apocynin-treated mice showed 50% less brain infarction and 70% less cleaved spectrin compared with WT mice. 19417757 2009
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases 		0.310 Biomarker group CTD_human Protection of podocytes from hyperhomocysteinemia-induced injury by deletion of the gp91phox gene. 20116427 2010
CUI: C3661525
Disease: Autosomal Recessive Chronic Granulomatous Disease
Autosomal Recessive Chronic Granulomatous Disease 		0.310 Biomarker disease CTD_human Successful unrelated bone marrow transplantation for a patient with chronic granulomatous disease and associated resistant pneumonitis and Aspergillus osteomyelitis. 11498749 2001
CUI: C3661525
Disease: Autosomal Recessive Chronic Granulomatous Disease
Autosomal Recessive Chronic Granulomatous Disease 		0.310 Biomarker disease CTD_human Point mutations in the promoter region of the CYBB gene leading to mild chronic granulomatous disease. 11122248 2000
CUI: C0011849
Disease: Diabetes Mellitus
Diabetes Mellitus 		0.360 Biomarker group CTD_human Oxidative stress-mediated thrombospondin-2 upregulation impairs bone marrow-derived angiogenic cell function in diabetes mellitus. 23723366 2013
CUI: C0018801
Disease: Heart failure
Heart failure 		0.370 Biomarker disease CTD_human MnSOD protects against COX1-mediated endothelial dysfunction in chronic heart failure. 20304815 2010
CUI: C0018802
Disease: Congestive heart failure
Congestive heart failure 		0.370 Biomarker disease CTD_human MnSOD protects against COX1-mediated endothelial dysfunction in chronic heart failure. 20304815 2010
CUI: C1863999
Disease: Peroxisome Biogenesis Disorder, Complementation Group D
Peroxisome Biogenesis Disorder, Complementation Group D 		0.400 Biomarker disease GENOMICS_ENGLAND
CUI: C0024138
Disease: Lupus Erythematosus, Discoid
Lupus Erythematosus, Discoid 		0.430 Biomarker disease GENOMICS_ENGLAND
CUI: C0024138
Disease: Lupus Erythematosus, Discoid
Lupus Erythematosus, Discoid 		0.430 Biomarker disease GENOMICS_ENGLAND
CUI: C0011853
Disease: Diabetes Mellitus, Experimental
Diabetes Mellitus, Experimental 		0.500 Biomarker disease CTD_human Resveratrol improves endothelial function: role of TNF{alpha} and vascular oxidative stress. 19478208 2009
CUI: C0035126
Disease: Reperfusion Injury
Reperfusion Injury 		0.500 Biomarker disease CTD_human Increased superoxide formation induced by irradiation preconditioning triggers kidney resistance to ischemia-reperfusion injury in mice. 19193722 2009