ADRB2, adrenoceptor beta 2, 154

N. diseases: 387; N. variants: 17
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.300 Biomarker disease BEFREE We analyzed angiographic results at follow up (including binary angiographic restenosis [BAR] and late-lumen-loss [LLL]) and clinical outcomes in hospital and at follow up, including target lesion revascularization (TLR), cardiovascular-, and all-cause mortality, myocardial infarction (MI) and stent thrombosis (ST). 30467994 2019
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.300 GeneticVariation disease BEFREE This study was undertaken to explore the relationship between LV remodeling after myocardial infarction and polymorphisms in the cardiac β1-AR and β2-AR genes. 21626217 2011
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.300 GeneticVariation disease BEFREE The Gln(27)Glu polymorphism but not the Arg(16)Gly polymorphism of the beta2-adrenergic receptor (ADRB2) gene appears to be associated with a broad range of aging-associated phenotypes, including cancers at different sites, myocardial infarction (MI), intermittent claudication (IC), and overall/healthy longevity in the Framingham Heart Study Offspring cohort. 20399803 2010
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.300 GeneticVariation disease BEFREE The results suggest that effects of single specific genetic variants of the ADRB2 and ACE genes on MI can be readily altered by gene-gene or/and gene-environmental interactions, especially in large heterogeneous samples. 20230274 2010
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.300 GeneticVariation disease LHGDN Association between polymorphisms in the beta2-adrenergic receptor gene with myocardial infarction and ischaemic stroke in women. 19190821 2009
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.300 GeneticVariation disease BEFREE Association of beta-1 and beta-2 adrenergic receptor gene polymorphisms with myocardial infarction. 19623647 2009
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.300 GeneticVariation disease BEFREE We evaluated the relationship between ADRB1 and ADRB2 haplotypes, cardiovascular risk (death, nonfatal myocardial infarction (MI), and nonfatal stroke), and atenolol-based vs. verapamil sustained-release (SR)-based antihypertensive therapy in 5,895 coronary artery disease (CAD) patients. 18615004 2008
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.300 GeneticVariation disease BEFREE Of the 92 polymorphisms tested, three that we previously reported on were associated with risk of MI, [pro12ala in the peroxisome proliferator activated-receptor gamma gene (odds ratio, OR = 0.75, P = 0.02); thr164ile in the beta-2 adrenergic receptor gene (OR = 0.14, P = 0.007); and ala23thr polymorphism in the eotaxin gene (OR = 1.87, P = 0.01)]. 16420563 2006
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.300 GeneticVariation disease BEFREE The present study found no evidence that haplotype for the two most common polymorphisms in the beta2AR are associated with development of MI in a Swedish hypertensive population, but haplotype may be associated with SBP. 15931235 2005
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.300 GeneticVariation disease LHGDN Haplotype analysis of the beta2 adrenergic receptor gene and risk of myocardial infarction in humans. 15520258 2005
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.300 Biomarker disease RGD Potent adenylate cyclase agonist forskolin restores myoprotective effects of ischemic preconditioning in rat hearts after myocardial infarction. 12400771 2002
CUI: C0027051
Disease: Myocardial Infarction
Myocardial Infarction
0.300 GeneticVariation disease BEFREE Four ADRB2 gene polymorphisms C19R (T-47C), T-20C, G16R (G+46A), Q27E (C+79G) were investigated in two studies: PEGASE, a study of moderate to severe hypertension (707 cases) conducted in France, and ECTIM, a case-control study of MI (1178 cases, 1187 controls) conducted in France, Northern Ireland and Scotland. 11821707 2002