ADRB2, adrenoceptor beta 2, 154

N. diseases: 387; N. variants: 17
Disease: Cardiomyopathies ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0878544
Disease: Cardiomyopathies
Cardiomyopathies 		0.310 Biomarker group CTD_human Disruption of type 5 adenylyl cyclase prevents β-adrenergic receptor cardiomyopathy: a novel approach to β-adrenergic receptor blockade. 25193472 2014
CUI: C0878544
Disease: Cardiomyopathies
Cardiomyopathies 		0.310 AlteredExpression group BEFREE These data demonstrate that the heart tolerates enhanced contractile function via 60-fold beta(2)AR overexpression without detriment for a period of >/=1 year and that higher levels of expression result in either aggressive or delayed cardiomyopathy. 10758054 2000