Disease: Male infertility ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0021364
Disease: Male infertility
Male infertility 		0.400 GeneticVariation phenotype BEFREE Additionally, none of the individual studies significantly affected the association between CYP1A1 rs4646903 polymorphism and male infertility, according to sensitivity analysis. 31374016 2019
CUI: C0021364
Disease: Male infertility
Male infertility 		0.400 Biomarker phenotype BEFREE Our results suggest CYP1A1 and COMT as new potential targets in treating male infertility. 28334509 2017
CUI: C0021364
Disease: Male infertility
Male infertility 		0.400 GeneticVariation phenotype BEFREE It is concluded that CYP1A1 gene polymorphisms and psychological distress act independently but do not interact with each other in pathogenesis of male infertility. 27220890 2016
CUI: C0021364
Disease: Male infertility
Male infertility 		0.400 GeneticVariation phenotype BEFREE Novel interactions were also observed between the MR of SEC and rs1042389 in CYP2B6, rs1048943 in CYP1A1, and rs1799931 in NAT2 on male infertility (P inter = 1.06 × 10(-4), 1.14 × 10(-3), 3.55 × 10(-3), respectively). 24488272 2014
CUI: C0021364
Disease: Male infertility
Male infertility 		0.400 GeneticVariation phenotype BEFREE Pooled odds ratios with 95% confidence intervals were used to assess the strength of the association between CYP1A1 3801T>C polymorphism and idiopathic male infertility risk. 24466186 2014
CUI: C0021364
Disease: Male infertility
Male infertility 		0.400 GeneticVariation phenotype BEFREE In conclusion, these results support that the CYP1A1 2A genotype polymorphism mainly contributes to idiopathic male infertility susceptibility in Asians but not in Caucasians. 24316127 2014
CUI: C0021364
Disease: Male infertility
Male infertility 		0.400 GeneticVariation phenotype BEFREE Smoking status modifies the relation between CYP1A1*2C gene polymorphism and idiopathic male infertility: the importance of gene-environment interaction analysis for genetic studies of the disease. 23548414 2013
CUI: C0021364
Disease: Male infertility
Male infertility 		0.400 GeneticVariation phenotype BEFREE We observed an association between male infertility and the GSTM1 and GSTT1 null deletion, but not with the CYP1A1 polymorphism in North Iranian men with idiopathic infertility. 21775774 2012
CUI: C0021364
Disease: Male infertility
Male infertility 		0.400 GeneticVariation phenotype BEFREE Further, when the variant genotypes were combined (CYP1A1*2A TC+CC) assuming a co-dominant allele effect, TC plus CC genotypes were also found to be significant with increased risk of male infertility (OR=1.57 95% CI=1.05-2.35 p=0.02). 19786002 2009
CUI: C0021364
Disease: Male infertility
Male infertility 		0.400 Biomarker phenotype CTD_human Negative effects of serum p,p'-DDE on sperm parameters and modification by genetic polymorphisms. 19303595 2009
CUI: C0021364
Disease: Male infertility
Male infertility 		0.400 GeneticVariation phenotype LHGDN Our results suggest that the CYP1A1 polymorphisms may contribute to the pathogenesis of male infertility in the Han-Chinese population. 17651397 2008
CUI: C0021364
Disease: Male infertility
Male infertility 		0.400 GeneticVariation phenotype BEFREE Our results suggest that the CYP1A1 polymorphisms may contribute to the pathogenesis of male infertility in the Han-Chinese population. 17651397 2008