Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.340 Biomarker group CTD_human Drug Metabolizing Enzyme and Transporter Gene Variation, Nicotine Metabolism, Prospective Abstinence, and Cigarette Consumption. 26132489 2015
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.340 Biomarker group BEFREE As a novel mechanism of lung tumorigenesis mediated by CYP2A6, we investigated the effects of cotinine on the suppression of apoptosis and promotion of lung tumor growth. 22687995 2012
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.340 Biomarker group CTD_human CYP2A6 overexpression in human lung cancers correlates with a high malignant status. 17549345 2007
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.340 AlteredExpression group LHGDN CYP2A6 overexpression in human lung cancers correlates with a high malignant status. 17549345 2007
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.340 GeneticVariation group LHGDN Genetic polymorphism of CYP2A6 as one of the potential determinants of tobacco-related cancer risk. 16176798 2005
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.340 Biomarker group CTD_human Genetic polymorphism of CYP2A6 as one of the potential determinants of tobacco-related cancer risk. 16176798 2005
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.340 GeneticVariation group LHGDN Evaluation of CYP2A6 genetic polymorphisms as determinants of smoking behavior and tobacco-related lung cancer risk in male Japanese smokers. 15308589 2004
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.340 Biomarker group CTD_human Role of human cytochrome P450 (CYP) in the metabolic activation of nitrosamine derivatives: application of genetically engineered Salmonella expressing human CYP. 12214673 2002
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.340 Biomarker group CTD_human Frequency of CYP2A6 gene deletion and its relation to risk of lung and esophageal cancer in the Chinese population. 11241319 2001
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.340 Biomarker group CTD_human CYP2A6 gene deletion reduces susceptibility to lung cancer. 10441482 1999