Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0376384
Disease: Nicotine Use Disorder
Nicotine Use Disorder
0.310 Biomarker phenotype CTD_human The Value of Biosamples in Smoking Cessation Trials: A Review of Genetic, Metabolomic, and Epigenetic Findings. 28472521 2018
CUI: C0376384
Disease: Nicotine Use Disorder
Nicotine Use Disorder
0.310 Biomarker phenotype CTD_human Variation in CYP2A6 and tobacco dependence throughout adolescence and in young adult smokers. 26644138 2016
CUI: C0376384
Disease: Nicotine Use Disorder
Nicotine Use Disorder
0.310 GeneticVariation phenotype BEFREE Nicotine use disorders are associated with polymorphisms in a cluster of nicotinic acetylcholine receptors on chromosome 15q24, and mutations that reduce the enzymatic activity of CYP2A6. 27338962 2016
CUI: C0376384
Disease: Nicotine Use Disorder
Nicotine Use Disorder
0.310 Biomarker phenotype CTD_human CYP2A6 and CYP2B6 genetic variation and its association with nicotine metabolism in South Western Alaska Native people. 22569203 2012
CUI: C0376384
Disease: Nicotine Use Disorder
Nicotine Use Disorder
0.310 Biomarker phenotype CTD_human Smoking cessation program and CYP2A6 polymorphism. 16720336 2006
CUI: C0376384
Disease: Nicotine Use Disorder
Nicotine Use Disorder
0.310 Biomarker phenotype CTD_human Genetically decreased CYP2A6 and the risk of tobacco dependence: a prospective study of novice smokers. 15564629 2004