Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0013146
Disease: Drug abuse
Drug abuse
0.340 GeneticVariation group BEFREE We investigate the mechanism of time-dependent inhibition (TDI) of human cytochrome P450 2D6 (CYP2D6) by 3,4-methylenedioxymethamphetamine (MDMA, ecstasy), one of the most widespread recreational drugs of abuse. 30114388 2018
CUI: C0013146
Disease: Drug abuse
Drug abuse
0.340 Biomarker group BEFREE Cytochrome P450 2D6 (CYP2D6) is a member of the cytochrome P450 (CYP) superfamily involved in the biotransformation of drugs and substances of abuse encountered in clinical toxicology. 25998998 2015
CUI: C0013146
Disease: Drug abuse
Drug abuse
0.340 Biomarker group CTD_human Impact of CYP2D6*10 on H1-antihistamine-induced hypersomnia. 17089107 2006
CUI: C0013146
Disease: Drug abuse
Drug abuse
0.340 Biomarker group BEFREE Inhibition of cytochrome P450 2D6 modifies codeine abuse liability. 10917405 2000
CUI: C0013146
Disease: Drug abuse
Drug abuse
0.340 Biomarker group BEFREE In human experimental studies, we have shown that CYP phenotype and genotype affect abuse liability of CYP2D6 metabolized drugs of abuse. 10911933 2000