Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse
0.740 Biomarker disease RGD CYP2E1 testis expression and alcohol-mediated changes of rat spermatogenesis indices and type I collagen. 23819932 2013
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse
0.740 Biomarker disease PSYGENET CYP2E1 gene promoter polymorphism -1293G>C increases the risk of essential hypertension in men with alcohol abuse. 24288753 2013
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse
0.740 Biomarker disease CTD_human Induction of blood lymphocyte cytochrome P450 2E1 in early stage alcoholic liver cirrhosis. 20843640 2011
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse
0.740 Biomarker disease PSYGENET Cytochrome P450 2E1 high activity polymorphism in alcohol abuse and end-organ disease. 16425414 2005
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse
0.740 AlteredExpression disease BEFREE Cytochrome P450 2E1 high activity polymorphism in alcohol abuse and end-organ disease. 16425414 2005
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse
0.740 Biomarker disease PSYGENET Examination of a CYP2E1 repeat polymorphism in a monkey model of alcohol abuse. 11505041 2001
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse
0.740 AlteredExpression disease BEFREE To further investigate autoantibodies against cytochrome P-450s during alcohol abuse, sera of rats chronically treated with ethanol in the total enteral nutrition model and sera from alcoholics with or without alcohol liver disease and from control subjects were analyzed by enzyme-linked immunosorbent assay and Western blotting for the presence of IgG against rat and human CYP2E1, rat CYP3A1, and human CYP3A4. 9927612 1999
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse
0.740 Biomarker disease PSYGENET To further investigate autoantibodies against cytochrome P-450s during alcohol abuse, sera of rats chronically treated with ethanol in the total enteral nutrition model and sera from alcoholics with or without alcohol liver disease and from control subjects were analyzed by enzyme-linked immunosorbent assay and Western blotting for the presence of IgG against rat and human CYP2E1, rat CYP3A1, and human CYP3A4. 9927612 1999
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse
0.740 GeneticVariation disease BEFREE The findings indicate that Caucasians carrying the Rsa I c2 allele of the CYP2E1 gene may be at higher risk of developing ALD if they abuse alcohol. 8747406 1995
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse
0.740 Biomarker disease PSYGENET The findings indicate that Caucasians carrying the Rsa I c2 allele of the CYP2E1 gene may be at higher risk of developing ALD if they abuse alcohol. 8747406 1995
CUI: C0085762
Disease: Alcohol abuse
Alcohol abuse
0.740 AlteredExpression disease BEFREE CYP2E1 expression was not detected in fetal liver, kidney, lung, placenta (18 weeks gestational age) or liver (6 weeks gestational age) obtained at termination of pregnancy where maternal alcohol abuse had been established. 1575782 1992