DBH, dopamine beta-hydroxylase, 1621

N. diseases: 202; N. variants: 26
Disease: Pheochromocytoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0031511
Disease: Pheochromocytoma
Pheochromocytoma 		0.340 AlteredExpression disease BEFREE We observed an increase of TH mRNA concentration without correlation with TH protein expression in primary cell culture of PHEO and PGL incubated with dexamethasone during 24 hours; no changes were monitored for PNMT and DBH at both mRNA and protein level in PHEO and PGL. 25946206 2015
CUI: C0031511
Disease: Pheochromocytoma
Pheochromocytoma 		0.340 Biomarker disease CTD_human Monoamine oxidase A down-regulation contributes to high metanephrine concentration in pheochromocytoma. 22569243 2012
CUI: C0031511
Disease: Pheochromocytoma
Pheochromocytoma 		0.340 AlteredExpression disease BEFREE However, the tyrosine hydroxylase, AADC and DBH mRNA concentrations in the pheochromocytomas were greater than those of the normal adrenal medullas. 9578504 1998
CUI: C0031511
Disease: Pheochromocytoma
Pheochromocytoma 		0.340 Biomarker disease BEFREE A full length dopamine-beta-hydroxylase (DBH) cDNA clone was isolated from a human pheochromocytoma lambda gt11 library. 3443096 1987
CUI: C0031511
Disease: Pheochromocytoma
Pheochromocytoma 		0.340 AlteredExpression disease BEFREE We determined the activity of DBH in the plasma of 8 patients with pheos, secondary to multiple endocrine neoplasia Type 2 (MEN II) (medullary carcinoma of the thyroid [MCT], pheochromocytoma(s), and parathyroid hyperplasia). 723634 1978