Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
It is concluded that ACE-DD genotype may be a risk factor for the causation and development of chronic kidney failure among hypertensive patients.
|
27050505 |
2016 |
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
This study compared the polymorphisms of angiotensin-converting enzyme (ACE), angiotensinogen (AGT) and angiotensin II type 1 receptor (AT1R) gene between type II diabetes with diabetic nephropathy (DN) in end-stage renal disease (ESRD) and those of the normal individuals in Taiwan.
|
12728975 |
2003 |
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
This study investigated whether in these patients disease outcome and response to treatment were affected by gender or insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene. deltaGFR (0.43 +/- 0.05 versus 0.48 +/- 0.08 ml/min per 1.73 m2) and incidence of ESRD (23 and 22%, respectively) were comparable in male and female patients.
|
10616844 |
2000 |
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Thirteen articles were identified for the analysis of the association between ACE I/D gene polymorphism and ESRD risk in IgAN patients.
|
23060471 |
2013 |
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Our data also suggest that an interaction effect may exist between ACE (I/D) and eNOS (G894 --> T) polymorphism in increasing the risk of vascular complications in ESRD patients.
|
18629615 |
2008 |
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
ACE gene polymorphism does not have a significant effect on the development of ESRD and the prevalence of LVH in patients with ADPKD.
|
14600431 |
2004 |
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
In conclusion, ID polymorphism of the ACE gene plays an important role in the pathogenesis of vascular access thrombosis in subjects undergoing hemodialysis for chronic renal failure.
|
11525534 |
2001 |
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Faster progression to ESRD is associated with the ACE genotype when the total population with ESRD and with the AGT genotype when patients with glomerulonephritis are considered.
|
11422735 |
2001 |
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
In this large series of ADPKD patients, we found no effect of the ACE (I/D) polymorphism on the age at ESRD, either alone or in combination with the G460W polymorphism of ADD.
|
13679477 |
2003 |
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Compared with DPP4i nonusers, DPP4i users had a lower risk of ESRD (hazard ratio, 0.81; 95% CI, 0.70-0.94; P=.04) and all-cause mortality (hazard ratio, 0.28; 95% CI, 0.23-0.34; P<.001) after adjustments for CKD, advanced CKD, and angiotensin-converting enzyme inhibitor or angiotensin II receptor blocker use.
|
30343892 |
2018 |
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The mean age to end-stage renal disease (ESRD) was 54 yr, with no significant difference between men and women and no association with the angiotensin-converting enzyme polymorphism.
|
11961010 |
2002 |
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Comparing patients with ESRD (IgAN-ESRD) and those without ESRD (IgAN-non ESRD), there was a significant increase only in the ACE DD genotype (P < 0.05) among the four gene polymorphisms.
|
21163122 |
2010 |
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The results of this study suggest that ACE gene insertion/deletion and angiotensinogen M235T polymorphisms contribute to the increased risk for the development of CRF, but the magnitude of the effect within subsets of patients with specific etiologies of CRF must be evaluated further.
|
10916074 |
2000 |
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
This study strongly suggests that PKD 1 patients homozygous for the deletion allele of the ACE gene are at increased risk of developing ESRF at a early age.
|
9291178 |
1997 |
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
These findings suggest that Japanese patients with PKD homozygous for the D allele of the ACE gene are at increased risk for developing ESRD at an early age.
|
11136175 |
2001 |
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Significant associations were observed between ACE I/D and G2350A polymorphisms and ESRD.
|
23477970 |
2015 |
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Our results suggest that polymorphisms at the AGT and ACE gene loci are important markers for predicting progression to chronic renal failure in Caucasian patients with IgA nephropathy.
|
9259580 |
1997 |
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The ACE genotypes did not differ among the groups of slow progressors (27.1% I/I, 44.8% I/D and 28.1% D/D), pts with ESRF before 63 years of age (23.6% I/I, 51.4% I/D and 25% D/D) and rapid progressors (20% I/I, 55% I/D and 25% D/D).
|
12697976 |
2003 |
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
This study was designed to evaluate the angiotensin-converting enzyme insertion/deletion (ACE-I/D), angiotensinogen (AGT) M235T, and angiotensin II receptor type 1 (ATR1) A1166C and type 2 (ATR2) C3123A gene polymorphisms as risk factors for progression to ESRD in patients with VUR.Methods.
|
19288324 |
2009 |
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The aim of this study was to investigate the distribution of angiotensin converting enzyme (ACE), angiotensinogen (AGT) and angiotensin receptor type 1 (ATR1) genetic polymorphisms in children affected by chronic renal failure due to renal hypodysplasia associated with posterior urethral valves or without urethral abnormalities.
|
16006956 |
2005 |
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The ACE genotype distribution in patients with end-stage renal failure at the time of data compilation was similar to that of the entire study population.
|
10430974 |
1999 |
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Twenty-one patients reached ESRD (II = 4, ID = 13, DD = 4; chi2 not significant), but ACE genotype had no significant effect on renal survival.
|
14686639 |
2003 |
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Two hundred and forty-six end-stage renal disease (ESRD) patients on peritoneal dialysis and 183 control subjects, all of Chinese origin, were genotyped for the ACE insertion/deletion (I/D) and the AGT M235T gene polymorphisms.
|
12675870 |
2003 |
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
A deletion polymorphism in the angiotensin-converting enzyme (ACE) gene has been reported to be a risk factor for progression to chronic renal failure in immunoglobulin A nephropathy (IgAN).
|
9590186 |
1998 |
Kidney Failure, Chronic
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
There was no significant relationship detected between the D allele of ACE, the C allele of AT1R or the T allele of AGT genes and response to steroid therapy, extent of renal dysfunction and the progression to ESRD.
|
16525944 |
2005 |