ACE, angiotensin I converting enzyme, 1636

N. diseases: 101; N. variants: 18
Source: CURATED ×
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C2678367
Disease: Renal Tubular Dysgenesis With Choanal Atresia And Athelia
Renal Tubular Dysgenesis With Choanal Atresia And Athelia 		0.300 GermlineCausalMutation disease ORPHANET Mutations in genes in the renin-angiotensin system are associated with autosomal recessive renal tubular dysgenesis. 16116425 2005
CUI: C0007786
Disease: Brain Ischemia
Brain Ischemia 		0.300 Biomarker disease CTD_human Meta-analysis of genetic studies in ischemic stroke: thirty-two genes involving approximately 18,000 cases and 58,000 controls. 15534175 2004
CUI: C0011071
Disease: Sudden death
Sudden death 		0.300 Biomarker phenotype CTD_human Mice with cardiac-restricted angiotensin-converting enzyme (ACE) have atrial enlargement, cardiac arrhythmia, and sudden death. 15331425 2004
CUI: C0032310
Disease: Pneumonia, Viral
Pneumonia, Viral 		0.300 Biomarker disease CTD_human ACE1 polymorphism and progression of SARS. 15381116 2004
CUI: C0235480
Disease: Paroxysmal atrial fibrillation
Paroxysmal atrial fibrillation 		0.300 Biomarker disease CTD_human Mice with cardiac-restricted angiotensin-converting enzyme (ACE) have atrial enlargement, cardiac arrhythmia, and sudden death. 15331425 2004
CUI: C0546126
Disease: Acute Confusional Senile Dementia
Acute Confusional Senile Dementia 		0.300 Biomarker disease CTD_human Alzheimer disease risk and genetic variation in ACE: a meta-analysis. 14872014 2004
CUI: C0750900
Disease: Alzheimer's Disease, Focal Onset
Alzheimer's Disease, Focal Onset 		0.300 Biomarker disease CTD_human Alzheimer disease risk and genetic variation in ACE: a meta-analysis. 14872014 2004
CUI: C0750901
Disease: Alzheimer Disease, Early Onset
Alzheimer Disease, Early Onset 		0.300 Biomarker disease CTD_human Alzheimer disease risk and genetic variation in ACE: a meta-analysis. 14872014 2004
CUI: C0751956
Disease: Acute Cerebrovascular Accidents
Acute Cerebrovascular Accidents 		0.300 Biomarker disease CTD_human Meta-analysis of genetic studies in ischemic stroke: thirty-two genes involving approximately 18,000 cases and 58,000 controls. 15534175 2004
CUI: C0917798
Disease: Cerebral Ischemia
Cerebral Ischemia 		0.300 Biomarker disease CTD_human Meta-analysis of genetic studies in ischemic stroke: thirty-two genes involving approximately 18,000 cases and 58,000 controls. 15534175 2004
CUI: C2585653
Disease: Persistent atrial fibrillation
Persistent atrial fibrillation 		0.300 Biomarker phenotype CTD_human Mice with cardiac-restricted angiotensin-converting enzyme (ACE) have atrial enlargement, cardiac arrhythmia, and sudden death. 15331425 2004
CUI: C3468561
Disease: familial atrial fibrillation
familial atrial fibrillation 		0.300 Biomarker phenotype CTD_human Mice with cardiac-restricted angiotensin-converting enzyme (ACE) have atrial enlargement, cardiac arrhythmia, and sudden death. 15331425 2004
CUI: C0021295
Disease: Infant, Premature, Diseases
Infant, Premature, Diseases 		0.300 Biomarker group CTD_human Angiotensin-converting enzyme DD genotype is associated with worse perinatal cardiorespiratory adaptation in preterm infants. 14657821 2003
CUI: C0035242
Disease: Respiratory Tract Diseases
Respiratory Tract Diseases 		0.300 Biomarker group CTD_human Angiotensin-converting enzyme DD genotype is associated with worse perinatal cardiorespiratory adaptation in preterm infants. 14657821 2003
CUI: C0268250
Disease: Gaucher Disease, Type 2 (disorder)
Gaucher Disease, Type 2 (disorder) 		0.300 Biomarker disease CTD_human Pulmonary hypertension in type 1 Gaucher's disease: genetic and epigenetic determinants of phenotype and response to therapy. 12359135 2003
CUI: C0268251
Disease: Gaucher Disease, Type 3 (disorder)
Gaucher Disease, Type 3 (disorder) 		0.300 Biomarker disease CTD_human Pulmonary hypertension in type 1 Gaucher's disease: genetic and epigenetic determinants of phenotype and response to therapy. 12359135 2003
CUI: C0005138
Disease: Berylliosis
Berylliosis 		0.300 Biomarker disease CTD_human Angiotensin-1 converting enzyme polymorphisms in chronic beryllium disease. 10194187 1999
CUI: C0546126
Disease: Acute Confusional Senile Dementia
Acute Confusional Senile Dementia 		0.300 Biomarker disease CTD_human Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease. 9916793 1999
CUI: C0546126
Disease: Acute Confusional Senile Dementia
Acute Confusional Senile Dementia 		0.300 Biomarker disease CTD_human Angiotensin-converting enzyme genotype is associated with Alzheimer disease in the Japanese population. 10643899 1999
CUI: C0750900
Disease: Alzheimer's Disease, Focal Onset
Alzheimer's Disease, Focal Onset 		0.300 Biomarker disease CTD_human Angiotensin-converting enzyme genotype is associated with Alzheimer disease in the Japanese population. 10643899 1999
CUI: C0750900
Disease: Alzheimer's Disease, Focal Onset
Alzheimer's Disease, Focal Onset 		0.300 Biomarker disease CTD_human Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease. 9916793 1999
CUI: C0750901
Disease: Alzheimer Disease, Early Onset
Alzheimer Disease, Early Onset 		0.300 Biomarker disease CTD_human Angiotensin-converting enzyme genotype is associated with Alzheimer disease in the Japanese population. 10643899 1999
CUI: C0750901
Disease: Alzheimer Disease, Early Onset
Alzheimer Disease, Early Onset 		0.300 Biomarker disease CTD_human Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease. 9916793 1999
CUI: C0848676
Disease: Subfertility, Male
Subfertility, Male 		0.300 Biomarker phenotype CTD_human Mice lacking angiotensin-converting enzyme have low blood pressure, renal pathology, and reduced male fertility. 8642790 1996
CUI: C0917731
Disease: Male sterility
Male sterility 		0.300 Biomarker phenotype CTD_human Mice lacking angiotensin-converting enzyme have low blood pressure, renal pathology, and reduced male fertility. 8642790 1996