DDX5, DEAD-box helicase 5, 1655

N. diseases: 77; N. variants: 3
Disease: Colorectal Carcinoma ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.030 Biomarker disease BEFREE This study not only reveals the novel functional of O-GlcNAcylation in regulating DDX5, but also reveals the carcinogenic effect of the OGT-DDX5 axis in colorectal cancer. 30484950 2019
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.030 AlteredExpression disease BEFREE Clinically, concomitant NEAT1 and DDX5 protein levels negatively correlated with the overall survival and disease-free survival of CRC patients. 30185232 2018
CUI: C0009402
Disease: Colorectal Carcinoma
Colorectal Carcinoma 		0.030 AlteredExpression disease BEFREE Interestingly, primary CRC tissues highly expressing ALDOA or DDX5 had poor outcome (<i>p</i><0.0001 for both OS and DFS for ALDOA; <i>p</i>=0.001 for OS; and <i>p</i>=0.011 for DFS for DDX5) compared with patients who had low expression of those proteins. 29988738 2018