DNMT1, DNA methyltransferase 1, 1786

N. diseases: 496; N. variants: 36
Disease: Lupus Erythematosus, Systemic ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.100 AlteredExpression disease BEFREE We show that decreased ERK pathway signaling in T cells results in decreased expression of DNA methyltransferase 1 and overexpression of the methylation-sensitive genes CD11a and CD70, similar to T cells in human lupus. 18523434 2008
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.100 Biomarker disease BEFREE We also determined DNA methyltransferase 1 (DNMT1) protein content in CD4(+) T cells of SLE patients. 17492476 2008
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.100 AlteredExpression disease LHGDN We also determined DNA methyltransferase 1 (DNMT1) protein content in CD4(+) T cells of SLE patients. 17492476 2008
CUI: C0024141
Disease: Lupus Erythematosus, Systemic
Lupus Erythematosus, Systemic 		0.100 GeneticVariation disease BEFREE The associations between DNMT1 polymorphisms and the clinical profiles of SLE were analyzed. 15375672 2004