DNMT3A, DNA methyltransferase 3 alpha, 1788

N. diseases: 350; N. variants: 56
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.330 Biomarker group CTD_human Genomic landscape of cutaneous T cell lymphoma. 26192916 2015
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.330 Biomarker group BEFREE We have used whole-genome bisulfite sequencing to comprehensively characterize the methylomes from Dnmt3a wildtype and Dnmt3a-deficient mouse lung tumors. 23284304 2012
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.330 AlteredExpression group LHGDN MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3B. 17890317 2007
CUI: C0024121
Disease: Lung Neoplasms
Lung Neoplasms
0.330 AlteredExpression group BEFREE By immunohistochemical analysis, we demonstrated that DNMT1, DNMT3a and DNMT3b proteins were highly expressed in a coordinate manner in lung tumors, particularly in smokers (P=0.037, by the Fisher exact test). 17140695 2007