DRD1, dopamine receptor D1, 1812

N. diseases: 181; N. variants: 8
Disease: Seizures ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036572
Disease: Seizures
Seizures 		0.310 GeneticVariation phenotype BEFREE The T allele of the rs686 polymorphism within DRD1 gene was significantly more frequent in patients with alcohol dependence (p = 0.0008), with a larger excess for patients with severe dependence (p = 6 x 10(-6)), and even more for patients with severe complications such as withdrawal seizures (p = 7 x 10(-7)). 18341651 2008
CUI: C0036572
Disease: Seizures
Seizures 		0.310 Biomarker phenotype CTD_human Dopaminergic modulation of pilocarpine-induced motor seizures in the rat: the role of hippocampal dopamine D1 receptors. 1451735 1992
CUI: C0036572
Disease: Seizures
Seizures 		0.310 Biomarker phenotype CTD_human Dopamine D1 and D2 receptors mediate opposite functions in seizures induced by lithium-pilocarpine. 1829682 1991