DRD1, dopamine receptor D1, 1812

N. diseases: 181; N. variants: 8
Disease: Cocaine Dependence ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence 		0.310 GeneticVariation disease BEFREE We observed that both DRD1 and DRD2 polymorphisms were associated with opiate and cocaine dependence (P < 0.05) in Caucasian subjects, but not African-American individuals. 24078558 2013
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence 		0.310 Biomarker disease CTD_human Dopamine D1 and D3 receptors are differentially involved in cue-elicited cocaine seeking. 20456009 2010
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence 		0.310 Biomarker disease CTD_human Addiction-related alterations in D1 and D2 dopamine receptor behavioral responses following chronic cocaine self-administration. 16541082 2007
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence 		0.310 Biomarker disease CTD_human Expression of mutant NMDA receptors in dopamine D1 receptor-containing cells prevents cocaine sensitization and decreases cocaine preference. 16014726 2005
CUI: C0600427
Disease: Cocaine Dependence
Cocaine Dependence 		0.310 Biomarker disease CTD_human A single in vivo exposure to cocaine abolishes endocannabinoid-mediated long-term depression in the nucleus accumbens. 15295029 2004