Anxiety Disorders
|
0.400 |
Biomarker
|
group |
BEFREE |
Altogether, the present findings suggested that the ADORA2A gene and the interaction of ADORA2A and DRD2 genes may play a role in anxiety disorders in children and adolescents with ADHD.
|
30946941 |
2019 |
Anxiety Disorders
|
0.400 |
Biomarker
|
group |
BEFREE |
We previously reported that dopamine D2 receptor knockout (D2R<sup>-/-</sup>) mice display increased anxiety and depression-like behaviors upon chronic stress.
|
28912499 |
2017 |
Anxiety Disorders
|
0.400 |
Biomarker
|
group |
BEFREE |
After adjusting for age, occupation, education, marital status, self-rating anxiety score, and disease status, we observed significant negative associations of catechol-O-methyltransferase (COMT), dopamine receptor D2 (DRD2) gene score and smoking cessation, as well as significant positive associations between ankyrin repeat and kinase domain containing 1 (ANKK1), dopamine transporter (SLC6A3), dopamine receptor D4 (DRD4) gene score and smoking cessation.
|
27490263 |
2016 |
Anxiety Disorders
|
0.400 |
Biomarker
|
group |
BEFREE |
It is hypothesized that dopaminergic genes-dopamine type-2 receptor (DRD2), aldehyde dehydrogenase 2 (ALDH2), and catechol-O-methyltransferase (COMT)-are associated with bipolar disorder (BP) and anxiety disorder (AD).
|
25430946 |
2015 |
Anxiety Disorders
|
0.400 |
Biomarker
|
group |
BEFREE |
Our study also provides further evidence that the ALDH2 and DRD2 genes interact in BP-II, particularly BP-II without AD.
|
23835015 |
2014 |
Anxiety Disorders
|
0.400 |
GeneticVariation
|
group |
BEFREE |
An association was detected between the DRD2 A1 allele and symptoms of depression and anxiety indexed using interview and parent report methods.
|
20526230 |
2010 |
Anxiety Disorders
|
0.400 |
Biomarker
|
group |
CTD_human |
Genetics of caffeine consumption and responses to caffeine.
|
20532872 |
2010 |
Anxiety Disorders
|
0.400 |
Biomarker
|
group |
BEFREE |
Findings in DRD2 became stronger when only anxiety disorder cases with comorbid alcohol use disorder were considered.
|
20122683 |
2010 |
Anxiety Disorders
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Caffeine-induced anxiety (VAS) was also associated with two-loci interactions of selected ADORA2A and DRD2 polymorphisms.
|
18305461 |
2008 |
Anxiety Disorders
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Although no DRD2 polymorphisms were associated with the risk of alcoholism, +32806C>T and Block2-ht1 showed associations (in dominant models) with both the state anxiety level scale (STAI-S) and the trait anxiety level scale (STAI-T) (P=0.004 and P=0.003, and P=0.01 and P=0.005, respectively).
|
18307984 |
2008 |
Anxiety Disorders
|
0.400 |
Biomarker
|
group |
CTD_human |
Caffeine-induced anxiety (VAS) was also associated with two-loci interactions of selected ADORA2A and DRD2 polymorphisms.
|
18305461 |
2008 |
Anxiety Disorders
|
0.400 |
GeneticVariation
|
group |
BEFREE |
The paper focuses on such candidate gene polymorphisms that alter alcoholism-related intermediate phenotypes including: dopaminergic system polymorphic variants (DRD2 -141C Ins/Del in promoter region, exon 8 and DRD2 TaqI A and DAT 40bp VNTR genes polymorphisms) that cause predisposition to severe alcoholism (haplotype Ins/G/A2); COMT Val158Met gene polymorphism related to differences in executive cognitive function and 5-HTT gene promoter polymorphism, which alters stress response and affects anxiety and dysphoria.
|
17079080 |
2006 |
Anxiety Disorders
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Subjects with the DRD2 Al allele compared to those without this allele had significantly higher scores on GHQ 2 (anxiety/insomnia), GHQ 3 (social dysfunction) and GHQ 4 (depression).
|
16632165 |
2006 |
Anxiety Disorders
|
0.400 |
GeneticVariation
|
group |
BEFREE |
However, for men, but not for women, we observed a strong and specific association between low neuroticism-anxiety and the A1+ allele of the DRD2 TaqI A polymorphism across two independent samples and across two alternative personality scales.
|
15812318 |
2005 |
Anxiety Disorders
|
0.400 |
GeneticVariation
|
group |
BEFREE |
Within the bupropion group, subgroup analyses with stratification by genotype demonstrated that craving, irritability, and anxiety were significantly attenuated only among subjects with DRD2-Taq1 A2/A2 genotypes.
|
14668077 |
2003 |
Anxiety Disorders
|
0.400 |
Biomarker
|
group |
BEFREE |
Earlier findings concerning association of DRD2 E8 A/A with increased anxiety and depression are replicated for the first time.
|
11692072 |
2001 |