Mental Depression
|
0.600 |
Biomarker
|
disease |
BEFREE |
Candidate gene study reveals DRD1 and DRD2 as putative interacting risk factors for youth depression.
|
27472173 |
2016 |
Mental Depression
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Findings for DAT1 intron8 were also significant for two EMD subscales, generalized anxiety (ηp(2)=.065) and depression (ηp(2)=.059), and for DRD2 rs2283265, depression (ηp(2)=.053).
|
24780147 |
2014 |
Mental Depression
|
0.600 |
Biomarker
|
disease |
PSYGENET |
Findings for DAT1 intron8 were also significant for two EMD subscales, generalized anxiety (ηp(2)=.065) and depression (ηp(2)=.059), and for DRD2 rs2283265, depression (ηp(2)=.053).
|
24780147 |
2014 |
Mental Depression
|
0.600 |
Biomarker
|
disease |
PSYGENET |
The A1 allele of the DRD2/ANKK1 Taq1A polymorphism (rs1800497) is associated with reduced striatal D(2/3) receptor binding in healthy individuals (Con) as well as depression and addiction.
|
23683269 |
2013 |
Mental Depression
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The A1 allele of the DRD2/ANKK1 Taq1A polymorphism (rs1800497) is associated with reduced striatal D(2/3) receptor binding in healthy individuals (Con) as well as depression and addiction.
|
23683269 |
2013 |
Mental Depression
|
0.600 |
Biomarker
|
disease |
PSYGENET |
Molecular genetic studies point to potential risk loci of psychotic depression shared with schizoaffective disorder (1q42, 22q11, 19p13), depression, bipolar disorder, and schizophrenia (6p, 8p22, 10p13-12, 10p14, 13q13-14, 13q32, 18p, 22q11-13) and several vulnerability genes possibly contributing to an increased risk of psychotic symptoms in depression (eg, BDNF, DBH, DTNBP1, DRD2, DRD4, GSK-3beta, MAO-A).
|
23512949 |
2013 |
Mental Depression
|
0.600 |
Biomarker
|
disease |
RGD |
Importantly, Par-4 and DRD2 mRNA levels significantly correlated with depression-like behaviors.
|
21596067 |
2011 |
Mental Depression
|
0.600 |
Biomarker
|
disease |
PSYGENET |
Association between DRD2/ANKK1 Taq1A genotypes, depression and smoking cessation with nicotine replacement therapy.
|
21540761 |
2011 |
Mental Depression
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Research implicates the A1 allele of the dopamine D2 receptor gene (DRD2) Taq1A polymorphism in the development of depression and anxiety.
|
20526230 |
2010 |
Mental Depression
|
0.600 |
Biomarker
|
disease |
PSYGENET |
Research implicates the A1 allele of the dopamine D2 receptor gene (DRD2) Taq1A polymorphism in the development of depression and anxiety.
|
20526230 |
2010 |
Mental Depression
|
0.600 |
Biomarker
|
disease |
BEFREE |
The present study builds off this literature and examines whether DRD2 moderates the effect of violent victimization on depression.
|
18501970 |
2009 |
Mental Depression
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
It was found that the combination of COMT Met allele and DRD2 T allele predicted more severe depression in those already affected but did not predict the risk of depression when compared to normal population.
|
18929622 |
2008 |
Mental Depression
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
A number of studies suggest that variants in dopamine receptor genes, such as DRD2, are associated with depression but it is unclear if such variants also modify the association between life events and depression.
|
17585060 |
2007 |
Mental Depression
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Subjects with the DRD2 Al allele compared to those without this allele had significantly higher scores on GHQ 2 (anxiety/insomnia), GHQ 3 (social dysfunction) and GHQ 4 (depression).
|
16632165 |
2006 |
Mental Depression
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Individuals high in trait depression or nicotine dependence or with at least one dopamine D(2) receptor A1 allele experienced greater EEG deactivation following abstinence, especially in the right hemisphere during the stressful task.
|
15203798 |
2004 |
Mental Depression
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Before paroxetine treatment, patients with the DRD2 A1+ allele (A1A2 genotype) compared to those with the A1- allele (A2A2 genotype) had higher total GHQ psychopathological scores (P=0.040) and higher GHQ subscale scores for anxiety/insomnia (0.046), social dysfunction (P=0.033) and depression (P=0.011).
|
12957328 |
2003 |
Mental Depression
|
0.600 |
Biomarker
|
disease |
BEFREE |
Earlier findings concerning association of DRD2 E8 A/A with increased anxiety and depression are replicated for the first time.
|
11692072 |
2001 |