DRD3, dopamine receptor D3, 1814

N. diseases: 199; N. variants: 13
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0036341
Disease: Schizophrenia
Schizophrenia 		0.500 Biomarker disease HPO
CUI: C1860861
Disease: TREMOR, HEREDITARY ESSENTIAL, 1
TREMOR, HEREDITARY ESSENTIAL, 1 		0.300 Biomarker disease CTD_human
CUI: C0011253
Disease: Delusions
Delusions 		0.120 Biomarker disease HPO
CUI: C0013362
Disease: Dysarthria
Dysarthria 		0.100 Biomarker disease HPO
CUI: C0018524
Disease: Hallucinations
Hallucinations 		0.100 Biomarker disease HPO
CUI: C0027562
Disease: Negativism
Negativism 		0.100 Biomarker phenotype HPO
CUI: C0234378
Disease: Static Tremor
Static Tremor 		0.100 Biomarker phenotype HPO
CUI: C0239842
Disease: Tremor of hands
Tremor of hands 		0.100 Biomarker phenotype HPO
CUI: C1866986
Disease: Social and occupational deterioration
Social and occupational deterioration 		0.100 Biomarker phenotype HPO
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.370 Biomarker disease PSYGENET Depression and psychotic symptoms that occur in a large proportion of AD patients have been associated with monoamine genes coding for metabolic enzymes (COMT), transporters (5-HTTLPR) and receptors (DRD1; DRD3). 17851196 2007
CUI: C0011570
Disease: Mental Depression
Mental Depression 		0.370 GeneticVariation disease BEFREE Depression and psychotic symptoms that occur in a large proportion of AD patients have been associated with monoamine genes coding for metabolic enzymes (COMT), transporters (5-HTTLPR) and receptors (DRD1; DRD3). 17851196 2007
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.360 GeneticVariation disease BEFREE Depression and psychotic symptoms that occur in a large proportion of AD patients have been associated with monoamine genes coding for metabolic enzymes (COMT), transporters (5-HTTLPR) and receptors (DRD1; DRD3). 17851196 2007
CUI: C0011581
Disease: Depressive disorder
Depressive disorder 		0.360 Biomarker disease PSYGENET Depression and psychotic symptoms that occur in a large proportion of AD patients have been associated with monoamine genes coding for metabolic enzymes (COMT), transporters (5-HTTLPR) and receptors (DRD1; DRD3). 17851196 2007
CUI: C0344315
Disease: Depressed mood
Depressed mood 		0.060 GeneticVariation phenotype BEFREE Depression and psychotic symptoms that occur in a large proportion of AD patients have been associated with monoamine genes coding for metabolic enzymes (COMT), transporters (5-HTTLPR) and receptors (DRD1; DRD3). 17851196 2007
CUI: C0686347
Disease: Tardive Dyskinesia
Tardive Dyskinesia 		0.100 Biomarker disease BEFREE Tardive dyskinesia and DRD3, HTR2A and HTR2C gene polymorphisms in Russian psychiatric inpatients from Siberia. 19439249 2009
CUI: C3714760
Disease: Drug-induced tardive dyskinesia
Drug-induced tardive dyskinesia 		0.100 Biomarker disease BEFREE Tardive dyskinesia and DRD3, HTR2A and HTR2C gene polymorphisms in Russian psychiatric inpatients from Siberia. 19439249 2009
CUI: C0392702
Disease: Abnormal involuntary movement
Abnormal involuntary movement 		0.020 GeneticVariation disease BEFREE DRD3 genotype and age at first antipsychotic treatment contributed significantly to total score on the Abnormal Involuntary Movements Scale (AIMS). 10395214 1999
CUI: C0233514
Disease: Abnormal behavior
Abnormal behavior 		0.050 GeneticVariation phenotype BEFREE Dopamine D3 receptor gene (DRD3) variants have been implicated in the pathogenesis of psychiatric disorders. 10490702 1999
CUI: C0004936
Disease: Mental disorders
Mental disorders 		0.040 GeneticVariation group BEFREE Dopamine D3 receptor gene (DRD3) variants have been implicated in the pathogenesis of psychiatric disorders. 10490702 1999
CUI: C0376338
Disease: Diagnosis, Psychiatric
Diagnosis, Psychiatric 		0.010 GeneticVariation disease BEFREE DRD3 variants were not associated with these symptomatologic factors, and consideration of possible stratification effects, such as sex and psychiatric diagnosis, did not reveal any association either. 10490702 1999
CUI: C0022658
Disease: Kidney Diseases
Kidney Diseases 		0.010 GeneticVariation group BEFREE Dopamine D3 receptor gene polymorphisms, blood pressure and nephropathy in type 1 diabetic patients. 15004255 2004
CUI: C0221765
Disease: Chronic schizophrenia
Chronic schizophrenia 		0.030 GeneticVariation disease BEFREE Dopamine receptor D3 genotype association with greater acute positive symptom remission with olanzapine therapy in predominately caucasian patients with chronic schizophrenia or schizoaffective disorder. 18320559 2008
CUI: C3494623
Disease: Mild dementia
Mild dementia 		0.010 GeneticVariation disease BEFREE Dopamine D3 receptor gene polymorphism influences on behavioral and psychological symptoms of dementia (BPSD) in mild dementia of Alzheimer's type. 19363270 2009
CUI: C3178789
Disease: Widespread Chronic Pain
Widespread Chronic Pain 		0.010 GeneticVariation disease BEFREE DRD3 Ser9Gly polymorphism is related to thermal pain perception and modulation in chronic widespread pain patients and healthy controls. 19464960 2009
CUI: C0149931
Disease: Migraine Disorders
Migraine Disorders 		0.030 GeneticVariation group BEFREE DRD3 genotype and allelic variants were not related to the risk for migraine in Caucasian Spanish people. 20236178 2010