Unipolar Depression
|
0.370 |
Biomarker
|
disease |
BEFREE |
In combination with previous studies, these results suggest that cariprazine has a unique pharmacological profile and distinct dopamine D3 receptor-dependent mechanism of action that may be beneficial in the treatment of schizophrenia, bipolar disorder, and major depressive disorder.
|
28531264 |
2017 |
Unipolar Depression
|
0.370 |
Biomarker
|
disease |
BEFREE |
Role of nicotine dependence in the association between the dopamine receptor gene DRD3 and major depressive disorder.
|
24927283 |
2014 |
Unipolar Depression
|
0.370 |
Biomarker
|
disease |
PSYGENET |
Role of nicotine dependence in the association between the dopamine receptor gene DRD3 and major depressive disorder.
|
24927283 |
2014 |
Unipolar Depression
|
0.370 |
GeneticVariation
|
disease |
BEFREE |
Altogether, 10 representative variants covering 95.4% of DRD3 gene variation were investigated for association with response to ECT in a sample of 104 (71 female, 33 male) Caucasian patients with pharmacorefractory major depression.
|
22093107 |
2013 |
Unipolar Depression
|
0.370 |
Biomarker
|
disease |
PSYGENET |
Altogether, 10 representative variants covering 95.4% of DRD3 gene variation were investigated for association with response to ECT in a sample of 104 (71 female, 33 male) Caucasian patients with pharmacorefractory major depression.
|
22093107 |
2013 |
Unipolar Depression
|
0.370 |
Biomarker
|
disease |
PSYGENET |
A follow-up case-control association study of tractable (druggable) genes in recurrent major depression.
|
21630437 |
2011 |
Unipolar Depression
|
0.370 |
Biomarker
|
disease |
PSYGENET |
In a sample of 308 Chinese Han patients with major depressive disorder, 13 single nucleotide polymorphisms (SNPs) in coding regions of six genes (MAOA, SLC6A2, TH, COMT, DRD2, DRD3) with minor allele frequencies >5% were successfully genotyped from an initial series of 35 SNPs in 11 candidate genes associated with catecholamine neurotransmission.
|
21680027 |
2011 |
Unipolar Depression
|
0.370 |
GeneticVariation
|
disease |
BEFREE |
Preliminary evidence for an association between a dopamine D3 receptor gene variant and obsessive-compulsive personality disorder in patients with major depression.
|
16583407 |
2006 |
Unipolar Depression
|
0.370 |
Biomarker
|
disease |
PSYGENET |
Preliminary evidence for an association between a dopamine D3 receptor gene variant and obsessive-compulsive personality disorder in patients with major depression.
|
16583407 |
2006 |
Unipolar Depression
|
0.370 |
GeneticVariation
|
disease |
BEFREE |
Antidepressive response to sleep deprivation in unipolar depression is not associated with dopamine D3 receptor genotype.
|
11287789 |
2001 |
Unipolar Depression
|
0.370 |
Biomarker
|
disease |
BEFREE |
The possible involvement of dopamine receptor D3 in unipolar (UP) major depression was investigated by a genetic association study of the D3 receptor gene locus (DRD3) on 36 UP patients and 38 ethnically matched controls.
|
10697826 |
1999 |
Unipolar Depression
|
0.370 |
GeneticVariation
|
disease |
BEFREE |
Pairwise linkage analyses were carried out between the D3 dopamine receptor gene locus (DRD3) and schizophrenia (including major depression among its pleiotropic manifestations).
|
8464957 |
1993 |