DRD4, dopamine receptor D4, 1815

N. diseases: 189; N. variants: 7
Disease: Attention Deficit Disorder ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0041671
Disease: Attention Deficit Disorder
Attention Deficit Disorder 		0.500 Biomarker disease CTD_human The interactions among organophosphate pesticide exposure, oxidative stress, and genetic polymorphisms of dopamine receptor D4 increase the risk of attention deficit/hyperactivity disorder in children. 29054088 2018
CUI: C0041671
Disease: Attention Deficit Disorder
Attention Deficit Disorder 		0.500 Biomarker disease RGD The usefulness of the spontaneously hypertensive rat to model attention-deficit/hyperactivity disorder (ADHD) may be explained by the differential expression of dopamine-related genes in the brain. 17395336 2007
CUI: C0041671
Disease: Attention Deficit Disorder
Attention Deficit Disorder 		0.500 Biomarker disease CTD_human Polymorphisms TaqI A of the DRD2, BalI of the DRD3, exon III repeat of the DRD4, and 3' UTR VNTR of the DAT: association with childhood ADHD in male African-Caribbean cocaine dependents? 17671965 2007
CUI: C0041671
Disease: Attention Deficit Disorder
Attention Deficit Disorder 		0.500 Biomarker disease CTD_human Transmission disequilibrium testing of dopamine-related candidate gene polymorphisms in ADHD: confirmation of association of ADHD with DRD4 and DRD5. 14699430 2004
CUI: C0041671
Disease: Attention Deficit Disorder
Attention Deficit Disorder 		0.500 Biomarker disease CTD_human The dopamine D4 receptor is essential for hyperactivity and impaired behavioral inhibition in a mouse model of attention deficit/hyperactivity disorder. 14699433 2004