DSC3, desmocollin 3, 1825

N. diseases: 103; N. variants: 1
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.330 Biomarker group CTD_human 5-Aza-2'-deoxycytidine-mediated reductions in G9A histone methyltransferase and histone H3 K9 di-methylation levels are linked to tumor suppressor gene reactivation. 16799634 2007
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.330 AlteredExpression group LHGDN We also used a quantitative real-time RT-PCR approach, and analyzed all breast tumor specimens for DSC3 expression. 16168112 2005
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.330 AlteredExpression group BEFREE We also used a quantitative real-time RT-PCR approach, and analyzed all breast tumor specimens for DSC3 expression. 16168112 2005
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.330 Biomarker group LHGDN Mutant p53 and aberrant cytosine methylation cooperate to silence gene expression. 12789271 2003
CUI: C1458155
Disease: Mammary Neoplasms
Mammary Neoplasms
0.330 AlteredExpression group BEFREE Northern analysis, quantitative real-time polymerase chain reaction assay and Western blot analysis showed that desmocollin 3 is present in normal and immortalized human mammary epithelial cells, but consistently exhibits a significant, and often complete, down-regulation in breast cancer cell lines and primary breast tumors, both at the mRNA and protein levels. 11408939 2001