Coronary Arteriosclerosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Nitric oxide (NO) has been shown to play a key role in the regulation of cardiac hypertrophy and fibrosis in response to myocardial ischemia in part by antagonizing the action of angiotensin II (Ang II).
|
15763077 |
2005 |
Coronary Arteriosclerosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Angiotensinogen, one of the most important proteins in the renin-angiotensin system, plays a key role in the progress of coronary heart disease and myocardial infarction (MI).
|
23666149 |
2013 |
Coronary Arteriosclerosis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The results suggested that the molecular variant of the angiotensinogen gene could be a new risk factor for coronary atherosclerosis.
|
7850980 |
1995 |
Coronary Arteriosclerosis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Endothelial nitric oxide synthase and angiotensinogen gene polymorphism in coronary artery diseases in Egypt.
|
20547537 |
2011 |
Coronary Arteriosclerosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Additionally, the protein level of angiotensinogen (AGT) in the ascending aorta and the plasma concentration of Ang II were detected by Western blot and radioimmunoassay, respectively, in ATAA and coronary heart disease patients.
|
25955575 |
2015 |
Coronary Arteriosclerosis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
A polymorphism of angiotensinogen gene codon 174 and coronary artery disease in Japanese subjects.
|
9822117 |
1998 |
Coronary Arteriosclerosis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The M235T polymorphism of the AGT gene modifies the risk of coronary artery disease associated with the presence of hypercholesterolemia.
|
18409009 |
2008 |
Coronary Arteriosclerosis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
AGT gene polymorphisms (M235T, T174M) are associated with coronary heart disease in a Chinese population.
|
22791700 |
2013 |
Coronary Arteriosclerosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
These 11 therapies were for patients with heart failure (angiotensin-converting-enzyme inhibitors, angiotensin II receptor blockers, aldosterone receptor antagonists and digoxin), stable coronary artery disease (intensive statin therapy), asthma exacerbations (early inhaled corticosteroids in the emergency department and anticholinergics), chronic obstructive pulmonary disease (long-acting muscarinic antagonists and long-acting beta-2 adrenoceptor agonists) and schizophrenia (second-generation antipsychotics and depot/maintenance antipsychotics).
|
30045724 |
2018 |
Coronary Arteriosclerosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
The beneficial effect of ACE/kininase II inhibitors or angiotensin II AT1 receptor antagonists in cardiac ischaemia is abolished in TK-deficient mice, suggesting a prominent role for TK and kinins in the cardioprotective action of these drugs.
|
23572029 |
2013 |
Coronary Arteriosclerosis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
In addition, most importantly, we found no interaction between angiotensin II type 1 receptor A1166C gene variation and angiotensin I-converting Insertion/Deletion polymorphism, either in connection with the risk of coronary artery disease or myocardial infarction.
|
9857918 |
1998 |
Coronary Arteriosclerosis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Angiotensinogen gene polymorphism is associated with insulin resistance in nondiabetic men with or without coronary heart disease.
|
9665229 |
1998 |
Coronary Arteriosclerosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Moreover, MI induced in renin and angiotensinogen double-transgenic (Tg) mice showed comparable effects to MI plus NTX mice, including advanced ventricular remodeling and enhancement of RAS, oxidative stress, and monocytes chemoattractant protein (MCP)-1.
|
22986786 |
2012 |
Coronary Arteriosclerosis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Interaction of gender, hypertension, and the angiotensinogen gene haplotypes on the risk of coronary artery disease in a large angiographic cohort.
|
18653189 |
2009 |
Coronary Arteriosclerosis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The M235T single nucleotide polymorphism in the angiotensinogen gene is associated with coronary artery calcium in patients with a family history of coronary artery disease.
|
23137822 |
2013 |
Coronary Arteriosclerosis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
In 257 Dutch IDDM patients (188 with urinary albumin excretion (UAE) <30 mg/24 h), logistic regression analysis was used to study the relationships among, on the one hand, the insertion/deletion gene polymorphism of the angiotensin-converting enzyme gene (ACE-ID), the M235T gene polymorphism of the angiotensinogen gene (AGT-M235T), and the A1166C gene polymorphism of the angiotensin type 1 receptor gene (AT1-A1166C), and, on the other hand, UAE, retinopathy, hypertension, and coronary heart disease.
|
10862638 |
2000 |
Coronary Arteriosclerosis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Quantitative assessment of the effect of angiotensinogen gene polymorphisms on the risk of coronary heart disease.
|
17846284 |
2007 |
Coronary Arteriosclerosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Coexistence effect of hypertension and angiotensin II on the risk of coronary heart disease: a population-based prospective cohort study among Inner Mongolians in China.
|
30917708 |
2019 |
Coronary Arteriosclerosis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The present study strengthens the hypothesis of an association of both angiotensinogen gene polymorphisms with the extent of coronary heart disease.
|
10488958 |
1999 |
Coronary Arteriosclerosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Therefore, we analyzed the angiotensinogen gene as a modifier gene for coronary heart disease risk in patients with familial hypercholesterolemia.
|
18300856 |
2008 |
Coronary Arteriosclerosis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The angiotensinogen M235T variant was analyzed in 871 consecutive patients with clinically suspected coronary artery disease submitted to coronary angiography study.
|
16045904 |
2005 |
Coronary Arteriosclerosis
|
0.100 |
Biomarker
|
disease |
BEFREE |
Genetic polymorphisms of angiotensin-2 type 1 receptor and angiotensinogen and risk of renal dysfunction and coronary heart disease in type 2 diabetes mellitus.
|
19327134 |
2009 |
Coronary Arteriosclerosis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
The relationship among angiotensinogen genes polymorphisms and hs-CRP and coronary artery disease.
|
30912862 |
2019 |
Coronary Arteriosclerosis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Association of angiotensinogen gene T235 variant with increased risk of coronary heart disease.
|
7783537 |
1995 |
Coronary Arteriosclerosis
|
0.100 |
GeneticVariation
|
disease |
BEFREE |
Relationship of the rs1799752 polymorphism of the angiotensin-converting enzyme gene and the rs699 polymorphism of the angiotensinogen gene to the process of in-stent restenosis in a population of Polish patients with stable coronary artery disease.
|
27162064 |
2016 |