AGT, angiotensinogen, 183

N. diseases: 765; N. variants: 43
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy
0.580 GeneticVariation disease BEFREE Binary logistic regression displays that the association of the ACE and AGT gene polymorphisms in DR patients is not significant after adjusting for confounding covariates in all the comparisons. 29378484 2018
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy
0.580 GeneticVariation disease BEFREE 311 T1DM patients were recruited for the assessment of ACE and AGT polymorphisms relating to DR. 29484134 2018
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy
0.580 AlteredExpression disease BEFREE Compared with normal rats, AGT and CD34 were expressed more frequently in DR rats. 29488353 2018
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy
0.580 Biomarker disease BEFREE Potential of angiotensin II receptor blockers in the treatment of diabetic retinopathy. 28363842 2017
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy
0.580 Biomarker disease BEFREE This study intends to explore the role of microRNA-29a (miRNA-29a) in the development of diabetic retinopathy by targeting AGT gene in a rat model. 28189547 2017
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy
0.580 Biomarker disease BEFREE Angiotensin II (Ang II), an active component of the RAS is increased in diabetic retina, and may play a significant role in neurovascular damage leading to the progression of DR. 28403787 2017
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy
0.580 Therapeutic disease RGD Despite evidence that hyperactivity of the vasodeleterious axis (ACE/angiotensin II (Ang II)/AT1 receptor) of the renin-angiotensin system (RAS) is associated with the pathogenesis of diabetic retinopathy (DR) use of the inhibitors of this axis has met with limited success in the control of this pathophysiology. 21792177 2012
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy
0.580 Biomarker disease CTD_human There is increasing interest in a pathogenetic role for angiotensin II in ischaemic retinopathies such as diabetic retinopathy and retinopathy of prematurity. 15387897 2004
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy
0.580 GeneticVariation disease LHGDN Renin-angiotensin system gene polymorphisms and retinopathy in chinese patients with type 2 diabetes. 12716844 2003
CUI: C0011884
Disease: Diabetic Retinopathy
Diabetic Retinopathy
0.580 GeneticVariation disease BEFREE In a Dutch IDDM population, including 69 patients with (incipient) diabetic nephropathy, the T-allele of the AGT-M235T polymorphism is associated with an elevated UAE and diabetic retinopathy and the CC-genotype of the AT1-A1166C polymorphism is associated with hypertension. 10862638 2000