AGT, angiotensinogen, 183

N. diseases: 765; N. variants: 43
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0878544
Disease: Cardiomyopathies
Cardiomyopathies
0.400 Biomarker group BEFREE We previously reported that neonatal blockade of angiotensin II AT<sub>1</sub> receptor prevents cardiac changes in 4 weeks rats with neonatal hyperoxia-induced cardiomyopathy, a recognized model of prematurity-related deleterious conditions. 31376367 2019
CUI: C0878544
Disease: Cardiomyopathies
Cardiomyopathies
0.400 Biomarker group BEFREE Angiotensin II receptor blocker LCZ696 attenuates cardiac remodeling through the inhibition of the ERK signaling pathway in mice with pregnancy-associated cardiomyopathy. 31649814 2019
CUI: C0878544
Disease: Cardiomyopathies
Cardiomyopathies
0.400 Biomarker group BEFREE Sulforaphane prevents angiotensin II-induced cardiomyopathy by activation of Nrf2 via stimulating the Akt/GSK-3ß/Fyn pathway. 29353218 2018
CUI: C0878544
Disease: Cardiomyopathies
Cardiomyopathies
0.400 Biomarker group BEFREE Obese Leptin resistant (db/db) mice suffering from DM2, were treated with angiotensin II (AT) for 4 weeks to enhance the development of cardiomyopathy. 30359575 2018
CUI: C0878544
Disease: Cardiomyopathies
Cardiomyopathies
0.400 Biomarker group BEFREE Obese Leptin resistant (db/db) mice characterized by DM2 were treated with angiotensin II (AT) for 4 weeks to enhance the development of cardiomyopathy. 30071860 2018
CUI: C0878544
Disease: Cardiomyopathies
Cardiomyopathies
0.400 Biomarker group BEFREE Treatment of young PAI-1<sup>-/-</sup> mice with Angiotensin II induced extensive hypertrophy and fibrotic cardiomyopathy, with increased cardiac apoptosis and both reactive and replacement fibrosis. 28588076 2017
CUI: C0878544
Disease: Cardiomyopathies
Cardiomyopathies
0.400 Biomarker group BEFREE A novel in vivo model consisting of subcutaneously delivered angiotensin II in MFS mice reproducibly causes accelerated aortic aneurysm formation and cardiomyopathy. 28347539 2017
CUI: C0878544
Disease: Cardiomyopathies
Cardiomyopathies
0.400 Biomarker group CTD_human Upregulation of vasopressin V2 and aquaporin 2 in the inner medullary collecting duct of cardiomyopathic hamsters is attenuated by enalapril treatment. 12145768 2002
CUI: C0878544
Disease: Cardiomyopathies
Cardiomyopathies
0.400 GeneticVariation group BEFREE Results indicate that the ACE I/D and angiotensinogen M235T and T174M polymorphisms are not related to HCM or DCM in the Japanese population, and that variants of these polymorphisms do not contribute to the genesis or progression of these cardiomyopathies. 9270088 1997
CUI: C0878544
Disease: Cardiomyopathies
Cardiomyopathies
0.400 GeneticVariation group BEFREE Because ACE polymorphism modulates local production of angiotensin II, a powerful coronary vasoconstrictor, it may influence left ventricular mass in general as well as in coexisting disease states such as hypertension and cardiomyopathy. 8869131 1995
CUI: C0878544
Disease: Cardiomyopathies
Cardiomyopathies
0.400 Biomarker group BEFREE The role of genetic variants in angiotensin I converting enzyme, angiotensinogen and the angiotensin II type-1 receptor in the pathophysiology of heart muscle disease. 8869132 1995