DSG3, desmoglein 3, 1830

N. diseases: 78; N. variants: 0
Disease: Bulla ×
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0005758
Disease: Bulla
Bulla 		0.020 Biomarker phenotype LHGDN Pemphigus vulgaris (PV) is an autoimmune blistering disease, characterized by the loss of cell-cell adhesion between epidermal keratinocytes and the presence of autoantibody against desmoglein 3 (Dsg3), which provides adhesive integrity to desmosomes between adjacent keratinocytes. 17428808 2007
CUI: C0005758
Disease: Bulla
Bulla 		0.020 Biomarker phenotype LHGDN These results also suggest that even a partial depletion of Dsg3 may contribute to blistering in PV patients. 17431647 2007