|
Kidney Failure, Chronic
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
The C allele in rs5186 in AGTR1 was associated with higher rates of death and major cardiovascular events in a meta-analysis of EA and AfAn patients with end-stage kidney disease.SNPs in ACE were associated with SCD.
|
29982608 |
2019 |
|
Kidney Failure, Chronic
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
In conclusion, AT1R A1166C gene polymorphism may not be correlated with ESRD risk in overall populations, Caucasians and Asians.
|
23902432 |
2013 |
|
Kidney Failure, Chronic
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
In the subjects with C1166 allele of AGTR1, several investigations reported increased risk for coronary artery disease, ischemic stroke, heart failure and end-stage renal disease but not for hypertension.
|
23176211 |
2013 |
|
Kidney Failure, Chronic
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
Among the ACE, AGT, AT1R and CYP gene polymorphisms, only the DD genotype may predispose the individual to increased risk of progression to ESRD in the Chinese population.
|
21163122 |
2010 |
|
Kidney Failure, Chronic
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
The angiotensin II Type 1 receptor (AT1R) A1166C (rs5186) genez polymorphism is equivocally associated with the patients' susceptibility to chronic kidney disease or end-stage renal disease.
|
19954723 |
2009 |
|
Kidney Failure, Chronic
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
This study was designed to evaluate the angiotensin-converting enzyme insertion/deletion (ACE-I/D), angiotensinogen (AGT) M235T, and angiotensin II receptor type 1 (ATR1) A1166C and type 2 (ATR2) C3123A gene polymorphisms as risk factors for progression to ESRD in patients with VUR.Methods.
|
19288324 |
2009 |
|
Kidney Failure, Chronic
|
0.300 |
GeneticVariation
|
disease |
LHGDN |
Genotyping was performed in 745 ESRD patients and 520 control subjects for the angiotensin-converting enzyme (ACE) I/D, angiotensinogen (AGT) M235T and angiotensin II type 1 receptor (AT1R) A1166C gene polymorphisms using polymerase chain reaction and gel analysis.
|
16384824 |
2006 |
|
Kidney Failure, Chronic
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
There was no significant relationship detected between the D allele of ACE, the C allele of AT1R or the T allele of AGT genes and response to steroid therapy, extent of renal dysfunction and the progression to ESRD.
|
16525944 |
2005 |
|
Kidney Failure, Chronic
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
Polymorphisms of ACE and AT1R genes additively contribute to QTc prolongation found in a great majority of ESRD patients.
|
16105049 |
2005 |
|
Kidney Failure, Chronic
|
0.300 |
GeneticVariation
|
disease |
LHGDN |
Polymorphisms of ACE and AT1R genes additively contribute to QTc prolongation found in a great majority of ESRD patients.
|
16105049 |
2005 |
|
Kidney Failure, Chronic
|
0.300 |
Biomarker
|
disease |
BEFREE |
The role of interaction of polymorphisms in the Renin-Angiotensin-System (RAS) with angiotensin converting enzyme (ACE) or angiotensin receptor (AGTR1) inhibitors (RAS inhibitors) is unknown, as is the role of such therapy in end stage renal disease (ESRD) patients.
|
15946912 |
2005 |
|
Kidney Failure, Chronic
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
We studied the angiotensin-converting enzyme (ACE), angiotensinogen (AGT), and angiotensin II type 1 receptor (AT1R) gene polymorphisms for association with susceptibility to primary vesicoureteral reflux (VUR) and disease progression in 74 Taiwanese children, including 16 with end-stage renal disease (ESRD), and 117 normal controls.
|
15045574 |
2004 |
|
Kidney Failure, Chronic
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
These results indicate that susceptibility to faster progression to ESRD is associated with the AT1R A1166C polymorphism.
|
12832734 |
2003 |
|
Kidney Failure, Chronic
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
Angiotensinogen and angiotensin II type 1 receptor gene polymorphism in patients with autosomal dominant polycystic kidney disease: effect on hypertension and ESRD.
|
12950120 |
2003 |
|
Kidney Failure, Chronic
|
0.300 |
GeneticVariation
|
disease |
LHGDN |
These results indicate that susceptibility to faster progression to ESRD is associated with the AT1R A1166C polymorphism.
|
12832734 |
2003 |
|
Kidney Failure, Chronic
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
This study compared the polymorphisms of angiotensin-converting enzyme (ACE), angiotensinogen (AGT) and angiotensin II type 1 receptor (AT1R) gene between type II diabetes with diabetic nephropathy (DN) in end-stage renal disease (ESRD) and those of the normal individuals in Taiwan.
|
12728975 |
2003 |
|
Kidney Failure, Chronic
|
0.300 |
Biomarker
|
disease |
RGD |
Angiotensin type 2 receptor antagonism confers renal protection in a rat model of progressive renal injury.
|
12089373 |
2002 |
|
Kidney Failure, Chronic
|
0.300 |
GeneticVariation
|
disease |
BEFREE |
We examined the A1166C polymorphism at the angiotensin II type 1 (AT1R) locus in patients with end-stage renal disease (ESRD).
|
12187084 |
2002 |
|
Kidney Failure, Chronic
|
0.300 |
Biomarker
|
disease |
BEFREE |
Polymorphism of angiotensin converting enzyme, angiotensinogen, and angiotensin II type 1 receptor genes and end-stage renal failure in IgA nephropathy: IGARAS--a study of 274 Men.
|
11053482 |
2000 |
|
Kidney Failure, Chronic
|
0.300 |
AlteredExpression
|
disease |
BEFREE |
It is concluded that AT1 receptor mRNA expression is low in glomeruli of patients with chronic renal disease.
|
10073605 |
1999 |