|
Essential Hypertension
|
0.600 |
Biomarker
|
disease |
BEFREE |
Angiotensin II type 1 receptor blockers (ARBs) are potentially useful in controlling the central blood pressure and arterial stiffness in mild to moderate essential hypertension, while the effects of ARBs in aged patients with essential hypertension are not entirely investigated.
|
30311805 |
2019 |
|
Essential Hypertension
|
0.600 |
Biomarker
|
disease |
BEFREE |
Angiotensin II type 1 receptor blocker losartan is potentially useful in controlling the central blood pressure and arterial stiffness in mild to moderate essential hypertension, while the effects of losartan in aged patients with essential hypertension are not entirely investigated.
|
30362602 |
2019 |
|
Essential Hypertension
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Among individuals with essential hypertension certain relationships were documented between rs5182 and rs5186 polymorphisms of AGTR1 gene and rs1799998 polymorphism of CYP11B2 gene on one hand and the volume of carotid bodies on one other.
|
29627490 |
2018 |
|
Essential Hypertension
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Hypomethylation of the Angiotensin II Type I Receptor (AGTR1) Gene Along with Environmental Factors Increases the Risk for Essential Hypertension.
|
28376480 |
2018 |
|
Essential Hypertension
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
AC+CC genotype of AT1R and noise were the risky factors of EH.
|
28157766 |
2017 |
|
Essential Hypertension
|
0.600 |
Biomarker
|
disease |
GENOMICS_ENGLAND |
Molecular and clinical analysis of TRPC6 and AGTR1 genes in patients with pulmonary arterial hypertension.
|
25603901 |
2015 |
|
Essential Hypertension
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Essential hypertension patients were genotyped for 11 polymorphisms of essential hypertension susceptibility genes including ADD1 (rs4961), GNB3 (rs5443, rs16932941), NOS3 (rs1799983, rs2070744), ACE (rs5186), AGTR1 (rs5186), AGT (rs699, rs4762), MR (rs5534), and TGFB1 (rs1800471).
|
26335431 |
2015 |
|
Essential Hypertension
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The present study suggests that CpG1 hypomethylation in the AGTR1 promoter is likely associated with the risk of EH in the population assessed.
|
26658476 |
2015 |
|
Essential Hypertension
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The aim of the present study is to assess the association between angiotensin II receptor type 1 polymorphisms and essential hypertension risk in Chinese Hani and Yi minorities.
|
25628312 |
2015 |
|
Essential Hypertension
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
A significant association was found in the AT1R genotypes (AC+CC) with essential hypertension (χ2 = 22.48, p = 0.0001).
|
24992666 |
2014 |
|
Essential Hypertension
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The AT1-AAs, AGTR1 gene polymorphisms and haplotypes solely or jointly have influences on candesartan-based antihypertensive response in patients with primary hypertension.
|
24131669 |
2014 |
|
Essential Hypertension
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The purpose of this study was to investigate the association between angiotensin II type 1 receptor (AT1R) gene A(1166)C variants with essential hypertension and some related parameters in a sample of Jordanian hypertensive patients.
|
24047102 |
2014 |
|
Essential Hypertension
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
To study the polymorphism of angiotensin-type 1 receptor (AT1R) gene A1166C in familial primary hypertension and its distribution in Han Yellow race of China.
|
24145933 |
2013 |
|
Essential Hypertension
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Functional polymorphisms that predispose to increased basal GRK4 activity both decrease dopamine receptor activity and increase angiotensin II type 1 (AT1) receptor activity and are associated with essential hypertension in a number of different human cohorts.
|
22407378 |
2012 |
|
Essential Hypertension
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Individuals carrying the mutated TT of AGT, DD of ACE and CC of AT1R genotypes had an 1.67 (P = 0.032), 3.09 (P < 0.001) and 3.45 (P < 0.001)-fold increased risk of HTA.
|
21779803 |
2012 |
|
Essential Hypertension
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The main aim of this study was to examine the association of A1166C polymorphism of angiotensin II type 1 receptor and telomere length with essential hypertension in Egyptian people.
|
21234654 |
2011 |
|
Essential Hypertension
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Correlation between HLA-DRB1, HLA-DQB1 polymorphism and autoantibodies against angiotensin AT(1) receptors in Chinese patients with essential hypertension.
|
21557256 |
2011 |
|
Essential Hypertension
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Angiotensin II type 1 receptor gene A1166C polymorphism and essential hypertension in Chinese: a meta-analysis.
|
20223791 |
2010 |
|
Essential Hypertension
|
0.600 |
Biomarker
|
disease |
BEFREE |
The aim of the study is to assess the association between the human AGTR1 gene and essential hypertension (EH) using a haplotype-based case-control study in Han Chinese subjects.
|
19833117 |
2010 |
|
Essential Hypertension
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The AGTR1 1166C allele when present in homozygous form may be associated with a form of essential hypertension characterized by high plasma aldosterone and low plasma renin levels, possibly due to increased AGTR1 mRNA levels and augmented angiotensin II action.
|
20027122 |
2010 |
|
Essential Hypertension
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
The A1166C polymorphism of the AT1 receptor gene is not associated with reduction of blood pressure after treatment with ACEI in patients with essential hypertension.
|
18575418 |
2008 |
|
Essential Hypertension
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Angiotensin II type 1 receptor (AGT1R) gene 1166A > C polymorphism has been shown to be associated with essential hypertension and aortic stiffness as measured by carotid femoral pulse wave velocity (PWV).
|
17227479 |
2007 |
|
Essential Hypertension
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Although polymorphisms in renin-angiotensin-aldosterone (RAA) system genes for angiotensinogen (AGT M235T), angiotensin-converting enzyme (ACE I/D), angiotensin II type 1 receptor (AT1 A/C1166), and aldosterone synthase (CYP11B2-344T/C) have been major targets for genetic investigation in association with essential hypertension (EH), the influence of these genetic factors is still to be determined.
|
17190732 |
2007 |
|
Essential Hypertension
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
These results suggest that the AGTR1 A1166C polymorphism is associated with essential hypertension and carotid atherosclerosis in a Chinese population.
|
16519598 |
2006 |
|
Essential Hypertension
|
0.600 |
GeneticVariation
|
disease |
BEFREE |
Associations of the angiotensin II type 1 receptor A1166C and the endothelial NO synthase G894T gene polymorphisms with silent subcortical white matter lesions in essential hypertension.
|
16109907 |
2005 |