E2F5, E2F transcription factor 5, 1875

N. diseases: 31; N. variants: 0
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.050 AlteredExpression disease BEFREE E2F5 was a direct target of miR-132, and downregulation of E2F5 caused by upregulation of miR-132 may contribute to the tumorigenesis of prostate cancer. 29393367 2018
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.050 AlteredExpression disease BEFREE In addition, knockdown of E2F5 and PFTK1 mimicked the tumor-suppressive effects of miR-1-3p overexpression on PCa progression. 30185212 2018
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.050 Biomarker disease BEFREE miR-154-5p may play an important role as an inhibitor of proliferation, migration and invasion of PCa by targeting E2F5 in PCa cell lines. 27074041 2017
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.050 Biomarker disease BEFREE Function of E2F5 and p38 in prostate cancer was investigated using siRNA-treatment of PC3 cell-line followed by analyses of associated components and cell cycle. 26919443 2016
CUI: C0600139
Disease: Prostate carcinoma
Prostate carcinoma
0.050 Biomarker disease BEFREE Analysis of genetic aberrations on chromosomal region 8q21-24 identifies E2F5 as an oncogene with copy number gain in prostate cancer. 23377984 2013