Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.070 AlteredExpression phenotype BEFREE Apolipoprotein M promotes proliferation and invasion in non-small cell lung cancers via upregulating S1PR1 and activating the ERK1/2 and PI3K/AKT signaling pathways. 29750961 2018
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.070 AlteredExpression phenotype BEFREE Overexpression of Gal-1 enhanced expression of S1PR1 in SGC-7901 cells, and increased cell invasion, while knockdown Gal-1 in MGC-803 cells reduced S1PR1 expression and diminished invasion. 30453284 2018
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.070 Biomarker phenotype BEFREE Biological functions of miR-542-3p and S1PR1 were analyzed using CKK-8, colony formation, migration, and invasion. 28121348 2017
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.070 AlteredExpression phenotype BEFREE Knockdown of Rad21 significantly attenuated the mutant p53-R248-induced invasion and the expressions of S1PR1 and THBS1. 28831167 2017
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.070 Biomarker phenotype BEFREE In conclusion, it was hypothesized that miR‑148a may potentially be used as a molecular agent for the prevention and treatment of invasion and metastasis in ovarian cancer, while S1PR1 may present a promising target for clinical applications. 26004261 2015
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.070 AlteredExpression phenotype BEFREE Overexpression of S1PR1 could reverse the inhibitory effect of miR-125b-1-3p on the invasion of trophoblast cells. 25251470 2014
CUI: C1269955
Disease: Tumor Cell Invasion
Tumor Cell Invasion
0.070 Biomarker phenotype BEFREE Furthermore, overexpression of SphK1 increased S1P levels, and the exogenous addition of S1P increased liver cell migration and invasion through the EDG1 receptor. 22098666 2012