Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.070 Biomarker group BEFREE Encoded by EEF1A1, the eukaryotic translation elongation factor eEF1α1 strongly promotes the heat shock response, which protects cancer cells from proteotoxic stress, following for instance oxidative stress, hypoxia or aneuploidy. 30224719 2018
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.070 AlteredExpression group BEFREE Reciprocal relationship of differential expression between EEF1A isoforms observed in multiple cancer types indicates opposing roles in cancer and needs further investigation. 29342219 2018
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.070 AlteredExpression group BEFREE Given that deregulated mRNA translation is a frequent feature of cancer and that eEF1A1 is highly expressed in many human tumours, these findings present new possibilities for the therapeutic targeting of EZH2 in AML. 28678185 2017
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.070 Biomarker group BEFREE These suggested eEF1A1 as a molecular marker to predict the selectivity and efficiency of 5-ALA based PDT in cancer therapy. 27150264 2016
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.070 AlteredExpression group BEFREE Nannocystin A (1) displayed differential activity across various cancer cell lines and EEF1A1 expression levels appear to be the main differentiating factor. 26179970 2015
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.070 GeneticVariation group BEFREE Translational infidelity and human cancer: role of the PTI-1 oncogene. 10216950 1999
CUI: C1306459
Disease: Primary malignant neoplasm
Primary malignant neoplasm
0.070 Biomarker group BEFREE Antisense inhibition of the PTI-1 oncogene reverses cancer phenotypes. 9465091 1998