|
Acne Vulgaris
|
0.100 |
GeneticVariation
|
disease |
GWASCAT |
Japanese GWAS identifies variants for bust-size, dysmenorrhea, and menstrual fever that are eQTLs for relevant protein-coding or long non-coding RNAs.
|
29855537 |
2018 |
|
Lymphocyte Count measurement
|
0.100 |
GeneticVariation
|
phenotype |
GWASDB |
The combination of a genome-wide association study of lymphocyte count and analysis of gene expression data reveals novel asthma candidate genes.
|
22286170 |
2012 |
|
Malignant Neoplasms
|
0.020 |
Biomarker
|
group |
BEFREE |
Accordingly, EEF1D is a potential target for cancer therapy.
|
29510727 |
2018 |
|
Malignant Neoplasms
|
0.020 |
AlteredExpression
|
group |
BEFREE |
However, there has been no information regarding the clinical significance of EF-1 delta mRNA expression in malignant tumours, including oesophageal carcinoma.
|
15199388 |
2004 |
|
Neurodevelopmental Disorders
|
0.010 |
Biomarker
|
group |
BEFREE |
However, mutations in the genes encoding these subunits EEF1B2 (eEF1Bα), EEF1D (eEF1Bδ), and VARS (valyl-tRNA synthetase) have also now been identified as causes of neurodevelopmental disorders.
|
30370994 |
2019 |
|
Liver carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Lower EEF1A1, EEF1B2, EEF1D and EEF1G levels were correlated with poor survival in glioma, while lower EEF1B2, EEF1D and EEF1E1 levels were correlated with better survival in hepatocellular carcinoma.
|
31639400 |
2019 |
|
Intellectual Disability
|
0.010 |
GeneticVariation
|
group |
BEFREE |
Biallelic loss of EEF1D function links heat shock response pathway to autosomal recessive intellectual disability.
|
30787422 |
2019 |
|
Neoplasms
|
0.010 |
AlteredExpression
|
group |
BEFREE |
EEF1D is upregulated in osteosarcoma and plays a tumor promoting role by facilitating Akt-mTOR and Akt-Bad signaling pathways.
|
29510727 |
2018 |
|
Osteosarcoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
EEF1D knockdown inhibited osteosarcoma cell proliferation, colony-forming ability, and cell cycle G2/M transition in vitro.
|
29510727 |
2018 |
|
Osteosarcoma of bone
|
0.010 |
Biomarker
|
disease |
BEFREE |
EEF1D knockdown inhibited osteosarcoma cell proliferation, colony-forming ability, and cell cycle G2/M transition in vitro.
|
29510727 |
2018 |
|
Primary malignant neoplasm
|
0.010 |
Biomarker
|
group |
BEFREE |
Accordingly, EEF1D is a potential target for cancer therapy.
|
29510727 |
2018 |
|
Childhood Osteosarcoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
EEF1D knockdown inhibited osteosarcoma cell proliferation, colony-forming ability, and cell cycle G2/M transition in vitro.
|
29510727 |
2018 |
|
Squamous cell carcinoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
EEF1D modulates proliferation and epithelial-mesenchymal transition in oral squamous cell carcinoma.
|
26823560 |
2016 |
|
Malignant transformation
|
0.010 |
AlteredExpression
|
phenotype |
BEFREE |
Alternative expression and sequence of human elongation factor-1 delta during malignant transformation of human bronchial epithelial cells induced by cadmium chloride.
|
20514991 |
2010 |
|
Spinal Muscular Atrophy
|
0.010 |
GeneticVariation
|
disease |
BEFREE |
Potentially interesting novel loci, including EEF1D, a translation elongation factor involved in the delivery of aminoacyl tRNAs to the ribosome (a process which has previously been implicated in genetic studies of spinal muscular atrophy) were identified but must be treated with caution due to concerns surrounding genomic location and platform suitability.
|
19997636 |
2009 |
|
Mammary Neoplasms
|
0.010 |
AlteredExpression
|
group |
LHGDN |
BMP-6 promotes E-cadherin expression through repressing deltaEF1 in breast cancer cells.
|
17997862 |
2007 |
|
Medulloblastoma
|
0.010 |
Biomarker
|
disease |
LHGDN |
We demonstrate that gain of 8q and expression levels of three 8q-mapped candidate genes (EEF1D, RPL30, RPS20) are associated with adverse outcome in medulloblastoma.
|
16968546 |
2006 |
|
Medulloblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
By applying CGH results to gene expression analysis of medulloblastoma, we identified three 8q-mapped genes that are associated with overall survival in the larger group of 64 patients (p < 0.05): eukaryotic translation elongation factor 1D (EEF1D), ribosomal protein L30 (RPL30), and ribosomal protein S20 (RPS20).
|
16968546 |
2006 |
|
Childhood Medulloblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
By applying CGH results to gene expression analysis of medulloblastoma, we identified three 8q-mapped genes that are associated with overall survival in the larger group of 64 patients (p < 0.05): eukaryotic translation elongation factor 1D (EEF1D), ribosomal protein L30 (RPL30), and ribosomal protein S20 (RPS20).
|
16968546 |
2006 |
|
Adult Medulloblastoma
|
0.010 |
Biomarker
|
disease |
BEFREE |
By applying CGH results to gene expression analysis of medulloblastoma, we identified three 8q-mapped genes that are associated with overall survival in the larger group of 64 patients (p < 0.05): eukaryotic translation elongation factor 1D (EEF1D), ribosomal protein L30 (RPL30), and ribosomal protein S20 (RPS20).
|
16968546 |
2006 |
|
Neoplasm Metastasis
|
0.010 |
AlteredExpression
|
phenotype |
LHGDN |
A higher expression of EF-1 delta was significantly correlated with lymph node metastases (P<0.05) and advanced stages (P<0.05).
|
15199388 |
2004 |
|
Esophageal carcinoma
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
Thus, we quantitated the expression of EF-1 delta in malignant and benign oesophageal tissues and associated these levels with clinicopathologic parameters of oesophageal carcinoma.
|
15199388 |
2004 |
|
Secondary malignant neoplasm of lymph node
|
0.010 |
AlteredExpression
|
disease |
BEFREE |
A higher expression of EF-1 delta was significantly correlated with lymph node metastases (P<0.05) and advanced stages (P<0.05).
|
15199388 |
2004 |