|
Liver neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Epidermal growth factor-like domain multiple (EGFL7) is overexpressed in less differentiated liver tumors.
|
30504933 |
2018 |
|
Liver neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
In summary, our results reveal a novel Hnf4α/miR-122/GALNT10 regulatory pathway that facilitates EGF miR-122 activation and hepatoma growth in HBV-associated hepatocarcinogenesis.
|
25422324 |
2015 |
|
Liver neoplasms
|
0.100 |
GeneticVariation
|
group |
BEFREE |
Epidermal growth factor (EGF) gene single-nucleotide polymorphism (SNP) is associated with an increased risk of hepatic tumors.
|
24703510 |
2014 |
|
Liver neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
However, the signaling pathways for EGF-induced motility of hepatoma cells remain undefined.
|
22701712 |
2012 |
|
Liver neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
The tyrphostin AG1478 inhibits proliferation and induces death of liver tumor cells through EGF receptor-dependent and independent mechanisms.
|
21864510 |
2011 |
|
Liver neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
About 59.09% of HCC liver tumour tissues assayed showed EGF protein expression.
|
19840254 |
2010 |
|
Liver neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Enhanced antitumor effect of EGF R-targeted p21WAF-1 and GM-CSF gene transfer in the established murine hepatoma by peritumoral injection.
|
11916239 |
2002 |
|
Liver neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
To understand the stability of rat EGF receptor mRNAs, we analyzed the expression of EGF receptor mRNAs in the hepatoma cell line, AH66 and liver cells.
|
9279516 |
1997 |
|
Liver neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
First, transfection experiments of the well-differentiated HepG2 human hepatoma cell line using different expression vectors of the HBV X-region demonstrated that the X-gene product is capable of inducing EGF-R gene overexpression; in addition, by using a stable in vitro expression system for HBV, it was shown that EGF-R gene expression in these cells is greater than in the uninfected parent cells, and that this results in a three-fold increase in 125I-EGF binding.
|
8396816 |
1993 |
|
Liver neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Epidermal growth factor (EGF) was found to induce a rapid 2-fold increase in the amount of insulin-like growth factor binding protein-1 (IGFBP-1) mRNA in human hepatoma Hep2G cells, and this was accompanied by a 2-fold increase in IGFBP-1 secretion.
|
1281991 |
1992 |
|
Liver neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Data are presented from a comparative research on expression of epidermal growth factor (EGF) receptors and response to EGF of six independently established cell lines derived from human hepatoma.
|
2544452 |
1989 |
|
Liver neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Since this autocrine growth under hormone-free conditions might play a basic role in malignant transformation, we studied the effect on cell replication and the presence of specific membrane receptors of epidermal growth factor (EGF) and insulin on a dedifferentiated human hepatoma cell line, named HA22T/VGH.
|
3040466 |
1987 |