|
Prostatic Neoplasms
|
0.400 |
AlteredExpression
|
group |
BEFREE |
Nevirapine induced extensive reprogramming of gene expression in vitro with up-regulation of genes that might be silenced during prostate tumor progression (i.e., K18, PSA and androgen receptor) and down-regulation of genes involved in the progression toward an androgen-independent phenotype (i.e., K5, EGFR1, EGF and VEGF-A).
|
19152342 |
2009 |
|
Prostatic Neoplasms
|
0.400 |
Biomarker
|
group |
BEFREE |
Decorin suppresses prostate tumor growth through inhibition of epidermal growth factor and androgen receptor pathways.
|
19794963 |
2009 |
|
Prostatic Neoplasms
|
0.400 |
GeneticVariation
|
group |
LHGDN |
Genetic polymorphism in EGF is associated with prostate cancer aggressiveness and progression-free interval in androgen blockade-treated patients.
|
18519765 |
2008 |
|
Prostatic Neoplasms
|
0.400 |
AlteredExpression
|
group |
LHGDN |
Site-specific androgen receptor serine phosphorylation linked to epidermal growth factor-dependent growth of castration-recurrent prostate cancer.
|
18511414 |
2008 |
|
Prostatic Neoplasms
|
0.400 |
AlteredExpression
|
group |
LHGDN |
Epidermal growth factor potentiates in vitro metastatic behaviour of human prostate cancer PC-3M cells: involvement of voltage-gated sodium channel.
|
18036246 |
2007 |
|
Prostatic Neoplasms
|
0.400 |
AlteredExpression
|
group |
LHGDN |
Diverse antiapoptotic signaling pathways activated by vasoactive intestinal polypeptide, epidermal growth factor, and phosphatidylinositol 3-kinase in prostate cancer cells converge on BAD.
|
16728406 |
2006 |
|
Prostatic Neoplasms
|
0.400 |
Biomarker
|
group |
BEFREE |
To provide real-time insights into these processes, we first validated use of an epidermal growth factor-conjugated fluorophore to illuminate orthotopic prostate tumors and their metastases in whole animal imaging.
|
17003496 |
2006 |
|
Prostatic Neoplasms
|
0.400 |
Biomarker
|
group |
CTD_human |
Epidermal growth factor promotes invasiveness of pancreatic cancer cells through NF-kappaB-mediated proteinase productions.
|
16340751 |
2006 |
|
Prostatic Neoplasms
|
0.400 |
Biomarker
|
group |
LHGDN |
Expression analysis of peptide growth factors VEGF, FGF2, TGFB1, EGF and IGF1 in prostate cancer and benign prostatic hyperplasia.
|
16820871 |
2006 |
|
Prostatic Neoplasms
|
0.400 |
PosttranslationalModification
|
group |
LHGDN |
Epidermal growth factor protects prostate cancer cells from apoptosis by inducing BAD phosphorylation via redundant signaling pathways.
|
16847055 |
2006 |
|
Prostatic Neoplasms
|
0.400 |
AlteredExpression
|
group |
LHGDN |
Epidermal growth factor modulates prostate cancer cell invasiveness regulating urokinase-type plasminogen activator activity. EGF-receptor inhibition may prevent tumor cell dissemination.
|
15886816 |
2005 |
|
Prostatic Neoplasms
|
0.400 |
Biomarker
|
group |
LHGDN |
Epidermal growth factor increases coactivation of the androgen receptor in recurrent prostate cancer.
|
14662770 |
2004 |
|
Prostatic Neoplasms
|
0.400 |
Biomarker
|
group |
BEFREE |
FD137, a nitrosourea appended to a quinazoline ring, was designed to simultaneously block epidermal growth factor receptor (EGFR)-mediated signaling and damage genomic DNA in refractory EGF-dependent prostate tumors.
|
14991862 |
2004 |
|
Prostatic Neoplasms
|
0.400 |
Biomarker
|
group |
BEFREE |
Our primary objectives were to: 1) develop a system for the study of prostatic tumor evolution; and 2) examine the role of the epidermal growth factor/epidermal growth factor receptor (EGF/EGFR) pathway in prostate tumor progression.
|
8077059 |
1994 |
|
Prostatic Neoplasms
|
0.400 |
AlteredExpression
|
group |
BEFREE |
Elevated levels of epidermal growth factor (EGF) and epidermal growth factor receptor (EGF-R) have been demonstrated in prostate cancer cell lines and clinical specimens suggesting a role for polypeptide growth factors in prostate tumor cell growth and invasion.
|
8290389 |
1994 |
|
Prostatic Neoplasms
|
0.400 |
AlteredExpression
|
group |
BEFREE |
Since EGF has also been found in prostatic tissues, the enhanced expression of the EGF-R gene may play a role in the growth of prostate tumors, possibly by an autocrine pathway.
|
1692888 |
1990 |