AHR, aryl hydrocarbon receptor, 196

N. diseases: 532; N. variants: 20
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0032285
Disease: Pneumonia
Pneumonia
0.330 Biomarker disease BEFREE Finally, AhR antagonist CH223191 and NAC inhibited BaP co-exposure with Der f 1-induced lung inflammation. 30982974 2019
CUI: C0032285
Disease: Pneumonia
Pneumonia
0.330 Biomarker disease BEFREE Finally, AhR knockout reduced ZnONPs-induced pulmonary inflammation, cytokine secretion and KYN production in mice, suggesting that AhR activation is involved in ZnONPs-induced cytokine secretion and pulmonary inflammation. 28285566 2017
CUI: C0032285
Disease: Pneumonia
Pneumonia
0.330 Biomarker disease CTD_human Thus, we tested the hypothesis that decreased activation of the pulmonary AhR augments hyperoxia-induced alveolar simplification and lung inflammation in newborn mice. 23337360 2013
CUI: C0032285
Disease: Pneumonia
Pneumonia
0.330 Biomarker disease BEFREE Interleukin-8 induction by the environmental contaminant benzo(a)pyrene is aryl hydrocarbon receptor-dependent and leads to lung inflammation. 18289803 2008