AHSG, alpha 2-HS glycoprotein, 197

N. diseases: 204; N. variants: 18
Source: ALL
Disease Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.100 Biomarker group BEFREE As a multifunctional protein, fetuin-A has positive effects on health such as calcification, cardiovascular diseases and tumor development processes with various mechanisms, whereas it plays a negative role in the processes of obesity, diabetes and fatty liver disease. 31232084 2019
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.100 Biomarker group BEFREE Serum Calcification Propensity and Fetuin-A: Biomarkers of Cardiovascular Disease in Kidney Transplant Recipients. 29996127 2018
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.100 Biomarker group BEFREE Fetuin-A plays a role in insulin resistance and cardiovascular disease. 28154244 2017
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.100 AlteredExpression group BEFREE Lower plasma fetuin-A levels were associated with an increased risk of all-cause and CVD mortality in patients with coronary artery disease independently of traditional CVD risk factors. 28912366 2017
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.100 AlteredExpression group BEFREE Therefore, we examined the effects of 6-month AEX+WL on plasma fetuin-A levels (36-48 hours after the last bout of exercise), aerobic capacity (VO<sub>2max</sub>), body composition, glucose tolerance, and insulin sensitivity (M) in 16 sedentary, overweight-obese older men (age = 60 ± 2 years, BMI = 31 ± 1 kg/m<sup>2</sup>) with no history of cardiovascular disease or diabetes. 28770230 2017
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.100 Biomarker group BEFREE Fetuin-A has a protective effect in cardiovascular disorders and is increased in hepatosteatosis. 28529199 2017
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.100 Biomarker group BEFREE Fetuin-A is an inhibitor of vascular calcification, and pentraxin 3 (PTX3) is produced at the site of inflammation, which is associated with cardiovascular disease (CVD). 29664315 2017
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.100 AlteredExpression group BEFREE Genetic variation and fetuin-A levels were assessed in 3299 community-living individuals (2733 Caucasians and 566 African Americans) 65 years of age or older, free of previous cardiovascular disease, who participated in the Cardiovascular Health Study (CHS) in 1992-1993. 26343871 2015
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.100 Biomarker group BEFREE These data provide evidence for the causal nature of the recently reported association between fetuin-A plasma levels and MI risk, thereby suggesting an involvement of fetuin-A in the pathogenesis of cardiovascular disease. 20031641 2009
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.100 Biomarker group BEFREE Vascular calcification inhibitors in relation to cardiovascular disease with special emphasis on fetuin-A in chronic kidney disease. 19004191 2008
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.100 AlteredExpression group BEFREE Fetuin A is an important mineralization inhibitor, and polymorphisms in the corresponding alpha2-Heremans-Schmid glycoprotein (AHSG) gene have been shown to be associated with serum fetuin A levels and free phosphate levels, as well as cardiovascular disease death. 17062776 2007
CUI: C0007222
Disease: Cardiovascular Diseases
Cardiovascular Diseases
0.100 Biomarker group BEFREE In a logistic regression model (N= 101), fetuin-A was significantly (P < 0.05) associated with the presence of carotid plaques independently of age, CVD, diabetes, S-albumin, gender, and inflammation. 15882283 2005